Results 71 to 80 of about 963,983 (301)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Reduced pattern training based on task decomposition using pattern distributor [PDF]

open access: yes, 2007
Task Decomposition with Pattern Distributor (PD) is a new task decomposition method for multilayered feedforward neural networks. Pattern distributor network is proposed that implements this new task decomposition method.
Guan, SU, Neo, T, Bao, C
core   +1 more source

A decomposition theory for matroids III. Decomposition conditions

open access: yesJournal of Combinatorial Theory, Series B, 1986
[For the former parts I and II see ibid. 39, 43-76 (1985; Zbl 0551.05033), and ibid. 39, 282-297 (1985; see the review above).] Part III presents some sufficient conditions to ensure that a decomposable minor of a matroid (with respect to the operation k-sum) induces a decomposition of the matroid itself.
openaire   +3 more sources

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Novel Deep Level Image State Ensemble Enhancement Method for M87 Imaging

open access: yesApplied Sciences, 2020
Standard spatial domain filters fail to adequately denoise and enhance the contrast of an image. These filters have drawbacks like oversmoothing, diminished texture, and lack of generative capabilities.
Timothy Ryan Taylor   +2 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Long-Term Fire Regime Modifies Carbon and Nutrient Dynamics in Decomposing Eucalyptus pilularis Leaf Litter

open access: yesFrontiers in Forests and Global Change, 2020
The changes in fire regimes expected under climate change are likely to disrupt the biogeochemical cycling of carbon (C) and nutrients in forest ecosystems.
Orpheus M. Butler   +4 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park   +5 more
wiley   +1 more source

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