Results 51 to 60 of about 22,752,852 (303)

Decomposition Analysis of Regional Electricity Consumption Drivers Considering Carbon Emission Constraints: A Comparison of Guangdong and Yunnan Provinces in China

open access: yesEnergies, 2023
Electricity consumption is closely linked to economic growth, social development, and carbon emissions. In order to fill the gap of previous studies on the decomposition of electricity consumption drivers that have not adequately considered carbon ...
Haobo Chen   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Income-Related Inequality in Health Care Utilization and Out-of-Pocket Payments in China: Evidence from a Longitudinal Household Survey from 2000 to 2015

open access: yesEconomies, 2022
In recent decades, China has experienced rapid economic growth and rising health inequality. The government has introduced a nationwide health care reform aimed at achieving affordable and equitable basic health care for all.
Miaoqing Yang, Guido Erreygers
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Socioeconomic Inequality in Knowledge About HIV and Its Contributing Factors Among Women of Reproductive Age in Sub-Saharan Africa: A Multicountry and Decomposition Analysis

open access: yesHIV/AIDS: Research and Palliative Care, 2023
Achamyeleh Birhanu Teshale, Getayeneh Antehunegn Tesema Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaCorrespondence: Achamyeleh Birhanu Teshale ...
Teshale AB, Tesema GA
doaj  

Global value chain participation impacts carbon emissions—Take the electro-optical equipment industry as an example

open access: yesFrontiers in Environmental Science, 2022
This study selects the electro-optical equipment manufacturing industry as an example to explore whether participation in the global value chain increases or mitigates a country’s carbon emissions and describes the impacting factors.
Xiaoming Ma   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Reduced pattern training based on task decomposition using pattern distributor [PDF]

open access: yes, 2007
Task Decomposition with Pattern Distributor (PD) is a new task decomposition method for multilayered feedforward neural networks. Pattern distributor network is proposed that implements this new task decomposition method.
Guan, SU, Neo, T, Bao, C
core   +1 more source

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