Results 41 to 50 of about 17,430 (270)

Oral Care in Hospital Settings: Breaking the Vicious Circle of Older Adult Deconditioning [PDF]

, 2021
Hospitalized older adults frequently develop aspiration pneumonia, swallowing dysfunction (dysphagia), and sarcopenia. In the current study, we propose a framework that incorporates these three factors into a vicious circle that leads to deconditioning ...
Montayre, Jed (R20033), John Parsons, Boyd, Michal, Oda, Keiko, Michal Boyd, Keiko Oda, Jed Montayre, Parsons, John   +7 more
core   +1 more source

Long-Term Bed Rest Delays the Circadian Phase of Core Body Temperature

Frontiers in Physiology, 2021
Spaceflight can be associated with sleep loss and circadian misalignment as a result of non-24 h light-dark cycles, operational shifts in work/rest cycles, high workload under pressure, and psychological factors.
Stefan Mendt, Katharina Brauns, Anika Friedl-Werner, Anika Friedl-Werner, Daniel L. Belavy, Daniel L. Belavy, Mathias Steinach, Thomas Schlabs, Thomas Schlabs, Andreas Werner, Andreas Werner, Hanns-Christian Gunga, Alexander C. Stahn, Alexander C. Stahn   +13 more
doaj   +1 more source

STRUCTURAL ALTERATIONS OF SKELETAL MUSCLE IN COPD

Frontiers in Physiology, 2014
Background: Chronic obstructive pulmonary disease (COPD) is a respiratory disease associated with a systemic inflammatory response. Peripheral muscle dysfunction has been well characterized in individuals with COPD and results from a complex interaction ...
Sunita eMathur, Dina eBrooks, Celso RF Carvalho   +2 more
doaj   +1 more source

Shifting from fear to safety through deconditioning-update

eLife, 2020
Aversive memories are at the heart of psychiatric disorders such as phobias and post-traumatic stress disorder (PTSD). Here, we present a new behavioral approach in rats that robustly attenuates aversive memories. This method consists of ‘deconditioning’
Bruno Popik, Felippe Espinelli Amorim, Olavo B Amaral, Lucas De Oliveira Alvares   +3 more
doaj   +1 more source

Comparative analysis of the body’s adaptation mechanisms

Annals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2022
This study presents the analysis of the mechanisms of adaptation or deconditioning of the organism in conditions of stress/immobilization. It is also, intended to present some specific aspects of these mechanisms in order to be able to predict the ...
Mihai Constantinescu
doaj   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey, Jessica Fitzpatrick, Maria Dall'Era, Charmayne Dunlop‐Thomas, Courtney Hoge, S. Sam Lim, Patricia P. Katz, Jinoos Yazdany, Laura C. Plantinga   +8 more
wiley   +1 more source

Biological Mechanisms Involved in Muscle Dysfunction in COPD: An Integrative Damage–Regeneration–Remodeling Framework

Cells
Skeletal muscle dysfunction is a major systemic manifestation of COPD that shapes symptoms, exercise tolerance and mortality. Current evidence can be integrated within a Damage–Regeneration–Remodeling framework linking mechanics and biology to clinical ...
Joaquim Gea, Mauricio Orozco-Levi, Sergi Pascual-Guàrdia, Carme Casadevall, César Jessé Enríquez-Rodríguez, Ramon Camps-Ubach, Esther Barreiro   +6 more
doaj   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Impact of physical deconditioning on ventricular tachyarrhythmias in trained athletes [PDF]

, 2004
ObjectivesThe purpose of this research was to evaluate the impact of athletic training and, in particular, physical deconditioning, on frequent and/or complex ventricular tachyarrhythmias assessed by 24-h ambulatory (Holter) electrocardiogram (ECG ...
Spataro, Antonio, Maron, Barry J., Biffi, Alessandro, Verdile, Luisa, Colivicchi, Furio, Marcello, Giuseppe, Pelliccia, Antonio, Fernando, Fredrick, Ciardo, Roberto, Ammirati, Fabrizio   +9 more
core   +1 more source

Basketball‐Related Injuries Increased in Pediatric Patients Presenting to United States Emergency Departments Between 2019 and 2023 With Strains and Sprains Being the Most Common Injury Types

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To estimate the number, risk factors, and types of basketball‐related injuries in pediatric patients who presented to United States emergency departments between 2019 and 2023, as estimated by the National Electronic Injury Surveillance System (NEISS).
Samisha M. Khangaonkar, Marshall S. Yuan, Calvin J. Wang, Ryan Cheng, Billy I. Kim, Joseph Manzi, Jay Moran, Andrew E. Jimenez   +7 more
wiley   +1 more source