Results 71 to 80 of about 1,642 (192)

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Liberation Through Narration: A Novel Humanistic Framework to Address Body Dissatisfaction

open access: yesThe Journal of Humanistic Counseling, EarlyView.
ABSTRACT Though body dissatisfaction is nuanced and pervasive, the magnitude of body dissatisfaction is undercut by essentialist conceptualizations of the body and medicalized metrics of wellness tied to disordered eating. Hence, there is a need for a contextualized and sustaining framework to address and promote healing from body dissatisfaction ...
Kim Hughes, Amber L. Pope
wiley   +1 more source

Economic Impact of a Deep Learning Algorithm for Automated Head and Neck Surgery Referral Triage

open access: yesThe Laryngoscope, EarlyView.
This prospective cost–benefit analysis evaluated a deep learning algorithm for automated referral triage across 214 new patient referrals at a high‐volume Head and Neck Surgical Oncology center operating under a fee‐for‐service model. The algorithm reduced referral triage labor by 98.5% (displacing 0.94 FTEs per division) and identified 80 verified ...
Stephanie Younan   +6 more
wiley   +1 more source

Climate‐Smart Destination Marketing and Community‐Based Tourism for Socio‐Economic Revitalization in Degraded Landscapes

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT As the global tourism industry confronts the existential imperatives of the Anthropocene, the remediation of degraded landscapes through regenerative economic models has emerged as a critical frontier in sustainability science. This research presents a rigorous empirical examination of the “restoration–revenue” paradigm, investigating the ...
Xin Sui, Tianchang Chen
wiley   +1 more source

Consumer Cultural Renaissance: Conceptualisation, Scale Development, and Validation

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT As incessant globalisation leads to the pervasive erosion of traditional Asian culture by Western consumerism, a recent phenomenon has emerged that allures Asian consumers to reconnect with their traditional culture via consumption. We postulate that this behaviour is rooted in a self‐identity, consumer cultural renaissance (CCR), that has not
Richard Lee   +3 more
wiley   +1 more source

Thiolate Salt Mediated Dynamic Silyl Ether Exchanges for Polymer Network Design and Deconstruction

open access: yesMacromolecular Rapid Communications, EarlyView.
This work introduces thiolate salts as mediators for dynamic silyl ether exchange. This platform enables the synthesis of reprocessable covalent adaptable polymer networks (CANs) and allows for sterically controlled, and tunable deconstruction of silyl ether‐containing thermosets.
Pierce T. Bombard   +9 more
wiley   +1 more source

Whole-genome combinatorial gene fusions generate novel genes for advanced microbial trait development. [PDF]

open access: yesProc Natl Acad Sci U S A
McNay MM   +5 more
europepmc   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

open access: yesMed Research, EarlyView.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang   +9 more
wiley   +1 more source

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