Results 121 to 130 of about 99,307 (266)

Multimodal Haptic Perception Through Synergistic Nanocomposite Sensor Arrays

Advanced Materials Technologies, EarlyView.
Multi‐modal fingertip haptics are advanced through a bioinspired &vertical‐via' electronic skin architecture. A confined PDMS/MWCNT/NiNP nanocomposite, sitting at the percolation threshold, enables tactile, thermal, and magnetic sensing. A unique via‐density gradient and dedicated &Un‐Touch' reference nodes provide robust spatial resolution and signal ...
Amos Bardea, Fernando Patolsky
wiley   +1 more source

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

Advanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen, Cong Minh Nguyen, Quang Thang Trinh, Minh Anh Huynh, Khanh Vinh Ho, Dang Co Pham, Dzung Dao, Sven Ingebrandt, Sina Jamali, Xuan Thang Vu, Nam‐Trung Nguyen, Tuan‐Khoa Nguyen   +11 more
wiley   +1 more source

Thickness‐Dependent Infrared Emissivity of Ultrathin Freestanding MoSiN Nanocomposite Membranes

Advanced Optical Materials, EarlyView.
ABSTRACT Metals and dielectrics show opposite trends in thickness‐dependent infrared emissivity: metallic films exhibit a rise in emissivity below a critical thickness, while dielectric films show a corresponding decline. For applications demanding both high emissivity and mechanical strength in membranes with nanoscale thickness, combining these ...
Reethu Sebastian, Amrid Amnache, Nadi Braidy, Luc G. Fréchette   +3 more
wiley   +1 more source

When Cubic is Not Isotropic: Phonon–Exciton Decoupling in CuInSnS4 Single Crystals

Advanced Optical Materials, EarlyView.
A cubic CuInSnS4 crystal does not fully play by cubic rules. While phonons follow the average iso‐tropic lattice symmetry, the disorder‐localized excitons break away, showing strong, and reproduci‐ble polarization‐dependent emission. This work shows how intrinsic cation disorder can turn a mac‐roscopically cubic material into a source of hidden ...
Lara Kim Linke, Yvonne Tomm, Xinyun Liu, Galina Gurieva, Daniel M. Többens, Pardis Adams, Michel Calame, Ryan W. Crisp, Jessica Boland, Seán Kavanagh, Susan Schorr, Mirjana Dimitrievska   +11 more
wiley   +1 more source

Circularly Polarized Red‐NIR Emission With High Dissymmetry Factor From Achiral [Mo6I8(OCOC2F5)6]2− Cluster Anion Embedded in a Bent‐Core Liquid Crystal Host

Advanced Optical Materials, EarlyView.
Associating a chiral bent core liquid crystal molecule, that self‐assembles into helical nanofilaments, with an achiral red‐NIR phosphorescent octahedral molybdenum cluster produces a hybrid material exhibiting efficient red‐NIR circularly polarized emission under UV excitation.
Jeanne Rebours, Shamima Akhter, Md Kamrul Hasan, Serge Paofai, Maria Amela‐Cortes, Marianne Estelle Prévôt, Yann Molard   +6 more
wiley   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal, Milan Patra, Rianita Mondal, Shubhasis Haldar   +3 more
wiley   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

Advanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch, Peter Goettig, Michael A. Nash, Juri Rappsilber, Nediljko Budisa   +4 more
wiley   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source