Results 81 to 90 of about 171,626 (298)

Measurement error when surveying issue positions: a MultiTrait MultiError approach

Political Science Research and Methods
Voters’ issue preferences are key determinants of vote choice, making it essential to reduce measurement error in responses to issue questions in surveys.
Kim Backström, Alexandru Cernat, Rasmus Sirén, Peter Söderlund   +3 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Biotic homogenization destabilizes ecosystem functioning by decreasing spatial asynchrony

, 2021
Our planet is facing significant changes of biodiversity across spatial scales. Although the negative effects of local biodiversity (α diversity) loss on ecosystem stability are well documented, the consequences of biodiversity changes at larger spatial ...
Wang, Shaopeng, Wilsey, Brian, et al.
core  

Nestedness across biological scales. [PDF]

, 2017
Biological networks pervade nature. They describe systems throughout all levels of biological organization, from molecules regulating metabolism to species interactions that shape ecosystem dynamics. The network thinking revealed recurrent organizational
Diego R. Barneche (599197), Mauricio Cantor, Sergio R. Floeter (503589), Brandt, Débora Y. C., Sebastián-González, Esther, Fábio G. Daura-Jorge (3719866), Coltri, P., Brandt, D., Pires, Mathias M., Nunes, Kelly, Kelly Nunes (255120), Sebastián González, Esther, Perez, S. Ivan, Guimaraes, P., Coltri, Patricia P., Floeter, S., Mauricio Cantor (3201021), Fábio G. Daura-Jorge, Paulo R Guimarães, Raimundo, Rafael L.G., Rafael L G Raimundo, Patricia P Coltri, Guimaraes, Paulo Roberto, Raimundo, Rafael L. G., Barneche, Diego R., Patricia P. Coltri, Esther Sebastián-González, Perez, Sergio Ivan, Sergio R. Floeter, Flavia M. D. Marquitti (2927196), Perez, S., Patricia P. Coltri (133430), Fábio G Daura-Jorge, Paulo R. Guimarães Jr. (214643), Paulo R. Guimarães, Floeter, Sergio R, Mathias M. Pires, Daura Jorge, Fábio G., Guimarães Jr., Paulo R., Mathias M. Pires (198573), Marquitti, Flavia M.D., Débora Y C Brandt, Rafael L. G. Raimundo, Raimundo, R., Pires, M., Brandt, Débora Y.C., Barneche, D., Marquitti, F., Débora Y. C. Brandt (3719860), Cantor, M., S Ivan Perez, Guimarães, Paulo R., Floeter, Sergio R., Débora Y. C. Brandt, Marquitti, Flavia M. D., Flavia M. D. Marquitti, Diego R Barneche, S. Ivan Perez (372534), Sergio R Floeter, Sebastian-Gonzalez, E., Mathias M Pires, Daura-Jorge, Fábio G., Cantor, Mauricio, Flavia M D Marquitti, Kelly Nunes, Rafael L. G. Raimundo (3719863), Daura-Jorge, F., Esther Sebastián-González (3719869), Diego R. Barneche, S. Ivan Perez, Nunes, K.   +70 more
core   +2 more sources

Discussion and prediction on decreasing flow stress scale effect

Transactions of Nonferrous Metals Society of China, 2006
Abstract Based on crystal plasticity theory and surface layer model, relation of flow stress to billet dimension and grain size was built, and rationality of derived relation was verified with tensile tests of different size billets. With derived expressions, relation of decreasing flow stress scale effect to billet dimension, grain size as well as ...
Yu SHEN, Hu-ping YU, Xue-yu RUAN
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Consumer Demand and Welfare under Increasing Block Pricing [PDF]

This paper argues that an increasing block pricing structure needs to be supplemented by allowances for household size and composition to be equitable.
Panos Pashardes, Soteroula Hajispyrou
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Climate responses to SATIRE and SIM-based spectral solar forcing in a 3D atmosphere-ocean coupled GCM

Journal of Space Weather and Space Climate, 2017
We apply two reconstructed spectral solar forcing scenarios, one SIM (Spectral Irradiance Monitor) based, the other the SATIRE (Spectral And Total Irradiance REconstruction) modeled, as inputs to the GISS (Goddard Institute for Space Studies) GCMAM ...
Wen Guoyong, Cahalan Robert F., Rind David, Jonas Jeffrey, Pilewskie Peter, Wu Dong L., Krivova Natalie A.   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source