Results 41 to 50 of about 43,171 (297)

Batallonaren ordena. Doneztebe, 1840 [PDF]

open access: yesFontes Linguae Vasconum, 2014
Goizuetako artxiboan aurkitutako dokumentu bat ematen da argitara. Testuaren izenburuan agertzen da zertsu izan daitekeen (batailoiaren ordena), data zehatza (1840ko urtarrilaren 12a) eta lekua (Doneztebe).
Juan Jose Zubiri
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

THE EVOLUTION OF THE INSTITUTION OF MARRIAGE IN SOVIET RUSSIA: FROM MARRIAGE REGRESSION TO CONSERVATIVE FAMILY (1917-1920-s)

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2016
The evolution of the ideological and legal concepts of marriage and family in Soviet Russia in the period from 1917 until the end of 1920-s is analyzed. It is revealed that one of the reasons for the transformation of ideas about marriage and the family ...
Viktor Vasilevich Nikulin
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

REGULARYFRAMWORK AND LEGAL BASE OF ELECTRONIC DOCUMENT CIRCULATION

open access: yesІнформаційні технології і засоби навчання, 2010
The general characteristic of legal base of electronic document circulation is presented in the article. It legislatively regulates the relations which connected with the information and information communication technologies. There is presented the list
Taisiia H. Omelchenko   +1 more
doaj  

The Italian national law on forests and forest supply chains: the landscape, the goods (and the woodlands), and the interventions to be set

open access: yesForest@, 2020
One of the implementing decrees of the Italian national forest law no. 34 of 2018 deals with the interventions to be set in the woodlands protected by the art. 136 of the national landscape and cultural heritage code (legislative decree no.
Sitzia T
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

THE TRANSFORMATION PHENOMENON IN THE HOLIDAY CULTURE OF PEASANTS FROM THE EUROPEAN NORTH OF RUSSIA IN 1911 – THE FIRST HALF OF THE 1930s (BASED ON PEASANT DIARIES)

open access: yesИзвестия высших учебных заведений. Поволжский регион: Гуманитарные науки, 2020
Background. The first third of the XX century in the history of our country is characterized by global changes in all spheres of society. They were associated with a change in the political system.
V. S. Zhukova
doaj   +1 more source

Speech Patterns in Litigation Documents (Exemplified by Decrees)

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание, 2020
he study focuses on speech patterns typically used in litigation documents issued at the stage of criminal proceeding initiation and pre-trial investigation, which belong to the genre of decree.
Yuliia V. Donskova
doaj   +1 more source

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