Results 51 to 60 of about 30,729 (244)

Probing the Physical Origin of the Balmer Decrement in the Broad-line Region of Nearby Active Galactic Nuclei via Spectral Variability

open access: yesThe Astrophysical Journal
To investigate the physical origin of the Balmer decrement in the broad-line region of active galactic nuclei (AGNs), we measure the temporal variability of the fluxes of the broad H β and H α emission lines using multiepoch spectroscopic data of low ...
Suyeon Son   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Experimental Investigation on Rotordynamic Characteristics and Rotor System Stability of a Novel Negative Dislocated Seal

open access: yesShock and Vibration, 2019
Air-induced force generated in seals is one key factor on the stability of the rotor system. In this paper, a novel negative dislocated seal (NDS) was developed in respect of dislocated bearing theory, to reduce hydrodynamic pressure effect and air ...
Dan Sun   +5 more
doaj   +1 more source

Effect of the insulation materials filling on the thermal performance of sintered hollow bricks under the air-conditioning intermittent operation

open access: yesCase Studies in Construction Materials, 2018
Wall insulation performance is an important factor affecting building energy consumption and indoor comfortable level. This study proposes that the insulation materials are filled into the cavities of the sintered hollow brick to replace the single ...
Chaoping Hou   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Response Surface Methodology for the Evaluation of Lysozyme Partitioning in Poly (Vinyl Pyrrolidone) and Potassium Phosphate Aqueous Two-Phase System [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2019
The partitioning of lysozyme and extraction yield in an aqueous two-phase system containing Poly Vinyl Pyrrolidone (PVP) K25 and potassium phosphate were investigated as a function of weight percent of salt and PVP in the feed, temperature, and pH.
Mohamad Mohamadpour   +3 more
doaj  

Factor structure and measurement invariance of a neuropsychological test battery designed for assessment of cognitive functioning in older Mexican Americans

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction The present study sought to investigate the measurement invariance of commonly used neuropsychological tests in an ethnically (Hispanic vs. non‐Hispanic) and linguistically (Spanish vs. English) diverse sample.
Brandon E. Gavett   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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