Results 41 to 50 of about 265,079 (219)

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

open access: yesBrain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña   +20 more
wiley   +1 more source

Noticias médicas

open access: yesRevista de la Facultad de Medicina, 1933
Decreto numero 604 de 1934  por el cual se nombran profesores de la Facultad de Medicina de la Universidad Nacional /  El V congreso medico ...
Facultad de Medicina Revista de la
doaj  

Atenção ao paciente vih/aids: legislação e biossegurança odontológica na Colombia [PDF]

open access: yes, 2006
Este artículo describe normas universales de bioseguridad en la atención odontológica, particularmente las referidas a la atención de personas infectadas con VIH/SIDA, al tiempo que pasa revista a leyes y decretos relativos al tema vigentes en Colombia ...
Acosta de Velásquez, Blanca Lucía
core   +1 more source

Land Reforms in Cuba: First Empirical Assessment on Productivity Using Crop‐Level Panel Data

open access: yesEconomics of Transition and Institutional Change, EarlyView.
ABSTRACT Land reforms implemented in Cuba since 2008 have aimed to increase agricultural production by distributing state‐owned idle lands with land‐use rights. The reforms restricted farmers with the rights from cultivating perennial and capital‐intensive crops.
Yoshihiko Hashiguchi   +1 more
wiley   +1 more source

De la resistencia a la adaptación. El pueblo de Santa Ana Tepetitlán, Jalisco, siglo XIX

open access: yesEspiral, 2006
Con la Independencia de nuestro país surge un nuevo grupo en el poder: los liberales y con ellos, el proceso de cambio de tenencia de la tierra, es decir, de una sociedad basada en organizaciones corporativas a una compuesta por ...
Laura Guillermina Gómez Santana
doaj  

Le contrôle de la constitutionnalité du décret avec force de loi [PDF]

open access: yes, 2014
This work focuses on the competence of the Constitutional Court to exercise judicial review of delegated legislation. Particularly analyzes whether the Chambers of Congress, or a quarter of its members, may request the Constitutional Court to challenge ...
Henríquez Viñas, Miriam
core   +2 more sources

The War of the Pacific and Chilean public revenues: Reallocation of the tax burden and institutional change

open access: yesThe Economic History Review, EarlyView.
Abstract A substantial body of literature has considered warfare a fundamental driver of fiscal capacity. We argue that the nature of the tax base available to governments can either foster or constrain the ability and incentives of central elites to impose their legitimacy once the war is over.
Oriol Sabaté, José Peres‐Cajías
wiley   +1 more source

Itinerario de un discurso normativo migratorio encorsetado; Itinerário de um discurso normativo migratório corseted; Itinerary of an enforced normative migration discourse

open access: yesRevista nuestrAmérica, 2019
Resumen: Este trabajo tiene como objetivo identificar los proyectos políticos estratégicos de carácter financiero globalizado, que influyen en las diferentes medidas que en materia de política migratoria se han dado desde el año 2014 hasta el 2018 ...
Elizabeth del Rosario Rojas   +1 more
doaj  

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