PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes
Advanced Science, EarlyView.A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li +10 more
wiley +1 more source
Enhanced Security of Bidirectional Communication in IoT-Driven Utility Networks Using Sertainty UXP and LoRaWAN. [PDF]
Sensors (Basel)Simin ZA +3 more
europepmc +1 more source
Advanced Science, EarlyView.This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen +15 more
wiley +1 more source
A Blockchain-Enabled Multi-Authority Secure IoT Data-Sharing Scheme with Attribute-Based Searchable Encryption for Intelligent Systems. [PDF]
Sensors (Basel)Zhang F, Xia X, Gao H, Ma Z, Chen X.
europepmc +1 more source
Advanced Science, EarlyView.This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley +1 more source
A secure and scalable blockchain-assisted authentication framework for decentralized IoT data management. [PDF]
Sci RepIswarya G, Vennila C.
europepmc +1 more source
MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes
Advanced Science, EarlyView.A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak +19 more
wiley +1 more source
Fine-Grained Personalized Data Aggregation Scheme with High Quality and Privacy Protection. [PDF]
Sensors (Basel)Xia Z, Murugesan RK.
europepmc +1 more source
Full‐Stack Architectures for Intelligent Brain‐Computer Interfaces
Advanced Science, EarlyView.System‐level overview of brain–computer interfaces (BCIs), illustrating the integration of neural signal acquisition, wireless transmission, and adaptive decoding. Advanced electrode, tissue interfaces, energy‐efficient communication, and robust algorithms collectively enable stable signal quality, real‐time processing, and closed‐loop operation ...
Hee Kyu Lee +9 more
wiley +1 more source
Privacy-preserving federated credit risk models: evaluating differential privacy and homomorphic encryption techniques. [PDF]
Sci RepNaresh VS, Ayyappa D.
europepmc +1 more source