Results 161 to 170 of about 10,693 (203)

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Securing IoMT data with Algorand blockchain, XChaCha20-Poly1305 encryption, and decentralized storage alternatives. [PDF]

Sci Rep
K D, P S UP.
europepmc   +1 more source

Analysis of Multiscale Condensation Phenomena Using a Zero‐Shot Computer Vision Framework

Advanced Science, EarlyView.
A zero‐shot computer vision framework quantifies multiscale condensation dynamics by automatically segmenting droplets and extracting physical parameters without labeled data. The workflow integrates data mining and statistical analysis to reveal droplet growth, coalescence statistics, and sweeping behaviors, enabling label‐free measurement of heat ...
Donghyeong Lee, Seokwan Roh, Jaewoo Jeong, Kuk‐Jin Yoon, Jungchul Lee, Youngsuk Nam   +5 more
wiley   +1 more source

A Secure and Efficient Authentication Scheme with Privacy Protection for Internet of Medical Things. [PDF]

Sensors (Basel)
Xu F, Wu J, An Q, Ziaur R.
europepmc   +1 more source

In Situ Disentangling Local Thermal and Photoelectron Contribution in Photoelectrochemical Reactions Based on Optical Microfiber Sensors

Advanced Science, EarlyView.
An in situ optical microfiber sensor capable of real‐time decoupling of photothermal and photoelectronic effects in photoelectrochemical reactions is presented. The approach utilizes highly sensitive modal interference to dynamically capture localized thermo‐optic signals from photothermal materials, thereby enabling quantitative discrimination of ...
Guangzheng Luo, Benfang Xu, Tiansheng Huang, Li‐Peng Sun, Bai‐Ou Guan   +4 more
wiley   +1 more source

In Situ Quantization with Memory‐Transistor Transfer Unit Based on Electrochemical Random‐Access Memory for Edge Applications

Advanced Science, EarlyView.
By combining ionic nonvolatile memories and transistors, this work proposes a compact synaptic unit to enable low‐precision neural network training. The design supports in situ weight quantization without extra programming and achieves accuracy comparable to ideal methods. This work obtains energy consumption advantage of 25.51× (ECRAM) and 4.84× (RRAM)
Zhen Yang, Yuxiang Yang, Baiqian Wang, Yaoyu Tao, Zelun Pan, Lei Cai, Teng Zhang, Longhao Yan, Xianbin Li, Yuchao Yang   +9 more
wiley   +1 more source

A blockchain-integrated chaotic fractal encryption scheme for secure medical imaging in industrial IoT settings. [PDF]

Sci Rep
Inam S, Kanwal S, Batool M, Al-Otaibi S, Jamjoom MM.   +4 more
europepmc   +1 more source

Ubiquitination‐Driven Reprogramming of Proteostasis in Metastasis

Advanced Science, EarlyView.
The DCAF12–TRiC/CCT axis is a key regulator of metastasis in cancer. By reprogramming proteostasis to ensure efficient protein folding, it drives progression through a dual mechanism: enhancing cancer cell motility and invasiveness while concurrently activating pro‐growth and survival pathways.
Dongping Wei, Jiayan Chen, Yaping Xu
wiley   +1 more source

Resilient Privacy Preservation Through a Presumed Secrecy Mechanism for Mobility and Localization in Intelligent Transportation Systems. [PDF]

Sensors (Basel)
Alanazi MD, Albekairi M, Abbas G, Alanazi TM, Kaaniche K, Elsayed G, Mercorelli P.   +6 more
europepmc   +1 more source

Orbital Hybridization‐Mediated Decoupling of Electrocatalytic Functions for Paired CO2 Electrosynthesis

Advanced Science, EarlyView.
This study constructs a dual‐scale Ag‐based catalyst on CeO2 nanorods via a facet‐guided strategy. This catalyst can induce a cascaded orbital hybridization effect, which synergistically optimizes oxygen vacancy stability, CO desorption kinetics, and charge transfer efficiency.
Youjia Wang, Bochen Tian, Yuxin Tian, Wenchao Wang, Xin Ma, Yansheng Liu, Junwei Hou   +6 more
wiley   +1 more source