Results 131 to 140 of about 381,401 (336)

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec, Ondrej Simonik, Zuzana Kratka, Lukas Ded, Jana Vondrakova, Maryam Qasemi, Barbora Bryndova, Michala Krejci, Daniela Spevakova, Vishma Pratap Sur, Radomir Kren, Tomas Hradec, Pavel Skrobanek, Ludmila Boublikova, Libor Zamecnik, Tomas Buchler, Jiri Neuzil, Pavla Postlerova, Katerina Komrskova   +18 more
wiley   +1 more source

Outcome parameters in studies investigating dry eye disease: A systematic literature review

Acta Ophthalmologica, EarlyView.
Abstract The development of effective therapeutics for dry eye disease (DED) is challenging due to its complex pathophysiology, heterogeneous patient presentation and the significant failure rate of previous clinical development programs. This underlines the importance of the selection of appropriate endpoints for clinical trials.
Viktoria Pai, Doreen Schmidl, Liudmyla Petric, Patrick Janku, Theresa Lindner, Ulrich Graf, Jacqueline Chua, Leopold Schmetterer, Gerhard Garhöfer   +8 more
wiley   +1 more source

What is the incidence and clinical significance of dry eye disease in patients treated with immune checkpoint inhibitors? A systematic review and meta‐analysis of ocular immune‐related adverse events

Acta Ophthalmologica, EarlyView.
Abstract Purpose Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but may cause immune‐related adverse events (irAEs), including dry eye disease (DED). This study aimed to quantify the incidence of ICI‐associated DED and to evaluate factors contributing to variability across studies.
Kai‐Yang Chen, Hoi‐Chun Chan, Chi‐Ming Chan   +2 more
wiley   +1 more source

Repeatability of keratometry depending on tear film osmolarity

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the repeatability of keratometry and astigmatism measurements of patients depending on the tear film osmolarity using three different devices. Methods In this study, 97 eyes of 97 patients with a mean age of 64.92 ± 12.07 years received three repeated measurements with the IOLMaster 700 (Carl Zeiss Meditec, Jena, Germany),
David Schneider, Klemens Paul Kaiser, Petra Davidova, Thomas Kohnen, Tyll Jandewerth   +4 more
wiley   +1 more source

Dry eye disease in episodic and chronic migraine: A cross-sectional clinic-based study

Cephalalgia Reports
Background Dry eye disease (DED) and migraine, two common disorders with public health concerns, may have a bidirectional relationship. Population-based studies have found that migraine patients have higher odds of DED and vice versa.
Bithi Chowdhury, Pradeep Kumar, Hemant Sharma, Debashish Chowdhury   +3 more
doaj   +1 more source

Dry eye disease symptoms and associated risk factors in a Norwegian clinical cohort

Acta Ophthalmologica, EarlyView.
Abstract Background The relationship between dry eye disease (DED) symptoms and different demographic, clinical and lifestyle factors remains poorly understood. Norway's cold climate and dry indoor air may accelerate tear evaporation, contributing to a very high meibomian gland dysfunction prevalence, as found in multiple studies.
Mazyar Yazdani, Fredrik A. Fineide, Reza A. Badian, Ayyad Zartasht Khan, Helge Rootwelt, Jan Terje Kvaløy, Tor Paaske Utheim   +6 more
wiley   +1 more source

Prevalence of Dry Eye Disease in a Community in Baguio City

Philippine Journal of Ophthalmology
Objective: This study determined the prevalence of dry eye disease (DED) in a community located in a high- altitude tropical city in the Philippines. Methods: This was a cross-sectional study conducted in Barangay Lualhati in Baguio City from March ...
Ruben Lim Bon Siong, Jayvee S. Rivera, Carlo Leandro R. Igama   +2 more
doaj  

Hierarchical Optimization of the As‐Rigid‐As‐Possible Energy

Computer Graphics Forum, EarlyView.
Abstract The As‐Rigid‐As‐Possible (ARAP) energy [SA07] has become a versatile ingredient in various geometry processing and machine learning methods. The classic method for its minimization is a block coordinate descent, alternating between local rotation estimation and a global linear solve, which converges slowly for large problem instances.
Hendrik Meyer, Bernd Bickel, Marc Alexa
wiley   +1 more source

A multi-institutional cohort study on risk of sleep disorders in dry eyes patients using TriNetX

Scientific Reports
To explore the relationship between DED and sleep disorders and examine the impact of DED’s duration on sleep disorders. This multi-institutional, retrospective cohort study used the TriNetX database.
Bing-Qi Wu, Hou-Ting Kuo, Alan Y. Hsu, Yi-Ching Shao, Ning-Yi Hsia, Chun-Ting Lai, Hsin Tseng, Chun-Chi Chiang, Chun-Ju Lin, Huan-Sheng Chen, Yu-Hsun Wang, Yi-Yu Tsai, Min-Yen Hsu, James Cheng-Chung Wei   +13 more
doaj   +1 more source

Development and implementation of a computerised clinical decision support system for hospital‐in‐the‐home patient identification

Internal Medicine Journal, EarlyView.
ABSTRACT Background Identification of appropriate patients for hospital‐in‐the‐home (HITH) remains a significant challenge. We hypothesise that a human‐centred design (HCD) approach can assist in developing a computerised clinical decision support system (CDSS) to address this issue via leveraging data within the electronic medical record (EMR).
Seok Ming Lim, Thomas Kitt‐Thompson, Douglas Forsyth Johnson, Michael Turner, Adam Boulton, Samantha Plumb, Daniel Capurro, Wen‐Kwang Lim   +7 more
wiley   +1 more source