Abstract Introduction Disentangling the role of the neighborhood environment in preeclampsia pathogenesis is crucial for addressing social and structural determinants of pregnancy health. Building on epidemiologic studies demonstrating environmental associations with preeclampsia, we used a machine learning approach to determine the relative importance
Chloé F. Paris +7 more
wiley +1 more source
Surface Cracking Mechanism of SP2215/Stellite-6 Components Fabricated by Laser-Directed Energy Deposition During High-Temperature Service. [PDF]
Che P +9 more
europepmc +1 more source
Abstract Macromolecular crowding modulates enzyme behavior in crowder‐ and protein‐specific ways, yet its impact on viral proteases, which are often key therapeutic targets, remains unclear. Here, we investigated the hepatitis C virus NS3/4A protease under increasing concentrations of polyethylene glycols (PEGs), ficoll, dextran, and lysozyme using ...
Małgorzata Lobka, Joanna Trylska
wiley +1 more source
Effect of Heat Input on Microstructure Evolution and High-Cycle Fatigue Behavior of Ti-6Al-4V Fabricated by Wire-Laser Directed Energy Deposition. [PDF]
Wang Z +9 more
europepmc +1 more source
Site‐specific O‐glycans influence lacritin structure and multimerization in tears
Abstract Lacritin is an abundantly expressed glycoprotein in tear fluid and plays key roles in immune response, tear secretion, and bacterial killing. These biological functions are tightly regulated through several biochemical mechanisms including multimerization, proteolysis, and alternative splicing, especially within its C‐terminal domain.
Vincent Chang +7 more
wiley +1 more source
Characteristics of Tear Film in Sjögren's Syndrome Patients as Measured by a Novel Tear Film Imager: A Pilot Study. [PDF]
Goulak AM +7 more
europepmc +1 more source
Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley +1 more source
The Effect of Varenicline Nasal Spray on the Signs and Symptoms of Dry Eye Disease and Tear Film Stability: A Randomized Controlled Trial. [PDF]
Stephenson PD, Matossian C.
europepmc +1 more source
Scheduling optimization of optical lens polishing
Abstract Optical systems have achieved notable progress in focusing and imaging technologies; however, manual grinding remains indispensable, resulting in elevated costs, extended timelines, and inefficiencies. These difficulties are compounded by operational constraints, uneven machine utilization, and risks of order delays and escalating expenses ...
Tzu‐Chin Lin, Bertrand M. T. Lin
wiley +1 more source

