Identification of Key Challenges and Optimization Options Along the Process Chain for the Manufacturing of a Thermally Optimized Injection Molding Tool Using the DED Process [PDF]
Thore Gericke +3 more
openalex +1 more source
Gestational age determination in pregnancies conceived via assisted reproductive technology
ABSTRACT Objectives To compare gestational age (GA) dating models for pregnancies conceived via assisted reproductive technology (ART), assess whether 14 or 15 days more accurately reflects the median follicular‐phase duration in ART pregnancies and evaluate whether the gestational timelines of ART pregnancies are comparable with that of spontaneously ...
M. Gjerdevik +3 more
wiley +1 more source
Perfluorohexyloctane eye drops in treating dry eye disease associated with meibomian gland dysfunction: a post hoc analysis by baseline severity. [PDF]
Liu Z, Ma L, Li Y, Tian L, Jie Y.
europepmc +1 more source
Single‐cell transcriptomics identifies that oral, intermittent fisetin supplementation improves endothelial function by targeting senescent endothelial cell‐derived senescence‐associated secretory phenotype (SASP) factors and CXCL12 in old animals. The SASP and specifically CXCL12 were found to drive age‐related endothelial dysfunction by promoting ...
Sophia A. Mahoney +14 more
wiley +1 more source
Large Language Models for Rapid Instrument Prototyping: Design and Structural Optimization of the Dry Eye Disease in Pregnancy Questionnaire (DED-PREG). [PDF]
Jaruchowska M +4 more
europepmc +1 more source
ABSTRACT Introduction Bipolar disorder (BD) and schizophrenia (SZ) are serious mental illnesses (SMI) with overlapping symptoms but distinct differences in onset and course. Sex differences are an area of growing interest in SMI. This study aims to examine potential interactions between sex and diagnosis across a broad range of variables, to compare ...
Maria Serra‐Navarro +35 more
wiley +1 more source
Managing dry eye disease - a review of selected traditional Chinese medicine and some of their metabolites focusing on molecular mechanisms and signaling pathways. [PDF]
Lu Y +5 more
europepmc +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Dry Eye Disease: Bridging Systemic Inflammation, Ocular Surface Biology, and Clinical Innovation. [PDF]
Gantz L.
europepmc +1 more source
ABSTRACT Youths’ socioeconomic status (SES) correlates with academic, cognitive, and neural outcomes, partly driven by influences on the developmental environment not captured by caregiver income and education alone. Leveraging Adolescent Brain Cognitive Development (ABCD) study data (M = 11.92 years; total n = 8,764), this study took an exploratory ...
Analia Marzoratti +4 more
wiley +1 more source

