Results 41 to 50 of about 29,957 (282)

How to deduplicate PCR [PDF]

Nature Methods, 2017
PCR duplicates—sequencing reads from the same original genomic fragment—can cause headaches. But there are remedies.
openaire   +2 more sources

Isosteric Substitution Enables Rational Design of Two‐Dimensional Energetic Crystals

Advanced Science, EarlyView.
Isosteric substitution transforms a classical nitro–amine motif into two‐dimensional aminofurazans with performance beyond TATB. ABSTRACT Two‐dimensional (2D) energetic crystals dissipate mechanical insult via interlayer slip, yet their molecular design space remains narrow.
Linyuan Wen, Wentong Tu, Tao Yu, Chao Chen, Zhixiang Zhang, Zhixiang Xie, Yingzhe Liu   +6 more
wiley   +1 more source

Deduplication-Aware Healthcare Data Distribution in IoMT

Mathematics
As medical sensors undergo expeditious advancements, there is rising interest in the realm of healthcare applications within the Internet of Medical Things (IoMT) because of its broad applicability in monitoring the health of patients.
Saleh M. Altowaijri
doaj   +1 more source

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

Advanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin, Zijie Chen, Yurong Li, Meijing Fang, Longji Shen, Yilong Su, Odin Zhang, Qinghan Wang, Qun Su, Jike Wang, Tingjun Hou, Yu Kang   +11 more
wiley   +1 more source

Exploring heterogeneity of unreliable machines for p2p backup

, 2013
P2P architecture is a viable option for enterprise backup. In contrast to dedicated backup servers, nowadays a standard solution, making backups directly on organization's workstations should be cheaper (as existing hardware is used), more efficient (as ...
Rzadca, Krzysztof, Skowron, Piotr
core   +1 more source

Large Language Model in Materials Science: Roles, Challenges, and Strategic Outlook

Advanced Intelligent Discovery, EarlyView.
Large language models (LLMs) are reshaping materials science. Acting as Oracle, Surrogate, Quant, and Arbiter, they now extract knowledge, predict properties, gauge risk, and steer decisions within a traceable loop. Overcoming data heterogeneity, hallucinations, and poor interpretability demands domain‐adapted models, cross‐modal data standards, and ...
Jinglan Zhang, Xinyi Chen, Xu Ye, Yulin Yang, Bin Ai   +4 more
wiley   +1 more source

Implications of deduplication on the detection rates of multidrug-resistant organism (MDRO) in various specimens: insights from the hospital infection surveillance program

Antimicrobial Resistance and Infection Control
Background Currently, different guidelines recommend using different methods to determine whether deduplication is necessary when determining the detection rates of multidrug-resistant organisms (MDROs).
Zhanjie Li, Dan Zhu, Xiaoju Ma, Feng Zang, Weihong Zhang, Can Luo, Chuanlong Zhu, Wensen Chen, Ping Zhu   +8 more
doaj   +1 more source

A Compression Technique Exploiting References for Data Synchronization Services [PDF]

, 2019
Department of Computer Science and EngineeringIn a variety of network applications, there exists significant amount of shared data between two end hosts. Examples include data synchronization services that replicate data from one node to another.
Nam, Wooseung
core  

Secure Cloud Storage with Client-Side Encryption Using a Trusted Execution Environment

, 2020
With the evolution of computer systems, the amount of sensitive data to be stored as well as the number of threats on these data grow up, making the data confidentiality increasingly important to computer users.
da Rocha, Marciano, Gorgonio, Kyller Costa, Pagno, Rodrigo Tomaz, Perkusich, Angelo, Valadares, Dalton Cézane Gomes, Will, Newton Carlos   +5 more
core   +1 more source

Innovative Artificial Intelligence‐Assisted Systems for Social Science Research: Architecture Design and Applied Practice

AI &Innovation, EarlyView.
ABSTRACT The rapid advancement of large language model (LLM) technology is profoundly transforming the practice of social science research. Scholarly discussions on Artificial Intelligence (AI)'s role in social science research can be organised into three levels: AI as a research tool, AI as a methodological infrastructure and AI as a quasi‐cognitive ...
Jie Xiong
wiley   +1 more source