Results 61 to 70 of about 595,263 (265)
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The 3D printing technique for sand mold exhibited the good response of precast concrete structure manufacturing process. The designed sandwich core structure, including solid core, diamond core, honeycomb core, pyramid core and round O core were ...
Khoa Vo Anh Pham +4 more
doaj +1 more source
Envisioning Answers: Unleashing Deep Learning for Visual Question Answering in Artistic Images [PDF]
In specialized fields, the accurate answering of visual questions is crucial for practical applications, and this study focuses on improving a visual question-answering model for artistic images by utilizing a dataset with both visual and knowledge-based
Erfan Zolghadriha +2 more
doaj +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Deep learning? What deep learning?
In teaching generally over the past twenty years, there has been a move towards teaching methods that encourage deep, rather than surface approaches to learning. The reason for this being that students, who adopt a deep approach to learning are considered to have learning outcomes of a better quality and desirability than those who adopt a surface ...
openaire +2 more sources
Multimedia Deep Learning [PDF]
By achieving breakthrough results on domains such as speech recognition, natural language processing, and computer vision, it is no surprise that deep neural networks are receiving a lot of attention these days. Specifically in the field of multimedia data analysis, there is a tremendous amount of multimedia big data that is being generated every day ...
openaire +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Accepted by ISAIC 2022, 8 pages, three figures.
openaire +2 more sources

