Results 231 to 240 of about 4,080,830 (296)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effect of Welding Heat Input on Microstructure and Properties of CGHAZ in Deep-Sea Oil and Gas Transportation Pipeline Steel. [PDF]

Materials (Basel)
Ran L, Liu S, Li B, Li Y, Hong R, Wang B, Liu Q, Jia S.   +7 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Looking beyond the vent to the environmental seascapes shaping deep-sea hydrothermal ecosystems. [PDF]

Sci Rep
Chapman ASA, Alfaro-Lucas JM, Beaulieu SE, Colaço A, Gebruk A, Haigh ID, Hilario A, Jamieson JW, Kihara TC, Sarrazin J, Tunnicliffe V, Bates AE.   +11 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Structured machine learning modeling to support conservation of deep-sea benthic biodiversity. [PDF]

Conserv Biol
Fonseca G, Vieira DC, Carneiro JC, Carreira RS, Ceccopieri M, Corbisier TN, Dalto AG, Figueiredo AG, Gallucci F, Gheller P, de Jesus SB, Lavrado HP, Lazzari L, Marcon EH, Moreira DL, de Moura RB, Pape E, Santarosa ACA, Dos Santos Filho JR, de Mello E Sousa SH, Vicente TM, Yaginuma LE, Yamashita C, Watanabe W.   +23 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

In situ deep-sea surface-enhanced Raman scattering sensor reveals cyanide as a key factor in cold seep nitrogen cycling. [PDF]

Sci Adv
Wang S, Zhao T, He W, Li F, Wang Z, Pan R, Li L, Xi S, Luan Z, Zhang Z, Li B, Chen L, Zhang X.   +12 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Review and Integrated Framework for Deep-Sea Mineral Resources, Ecological Influence, and Future Development. [PDF]

Int J Microbiol
Liu J, Wang C, Etim IN, Zhang R, Sand W, Wang X, Yang L, Ge Y, Liu J.   +8 more
europepmc   +1 more source