Results 211 to 220 of about 241,500 (289)

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

Trajectory Tracking Control for Subsea Mining Vehicles Based on Fuzzy PID Optimised by Genetic Algorithms. [PDF]

Sensors (Basel)
Bu H, Wu M, Liu B, Yan Z.
europepmc   +1 more source

The Challenge of Handling Structured Missingness in Integrated Data Sources

Advanced Intelligent Discovery, EarlyView.
As data integration becomes ever more prevalent, a new research question that emerges is how to handle missing values that will inevitably arise in these large‐scale integrated databases? This missingness can be described as structured missingness, encompassing scenarios involving multivariate missingness mechanisms and deterministic, nonrandom ...
James Jackson, Marius Hofert, Eleni‐Rosalina Andrinopoulou, Niels Hagenbuch, Sarah McGough, Chris Harbron, Robin Mitra   +6 more
wiley   +1 more source

Benthic Microbial Community Features and Environmental Correlates in the Northwest Pacific Polymetallic Nodule Field, with Comparative Analysis Across the Pacific. [PDF]

Microorganisms
Li Z, Yang J, He X, Zhao Z, Xia J.
europepmc   +1 more source

Advancements in Graphdiyne‐Based Multiscale Catalysts for Green Hydrogen Energy Conversion

Advanced Intelligent Discovery, EarlyView.
This review systematically explores the fundamental characteristics of graphdiyne (GDY), cutting‐edge field of GDY‐based multiscale catalysts within sustainable energy conversion systems.Special emphasis is placed on the structure‒property relationships in different reactions.
Qian Xiao, Lu Qi, Siao Chen, Yurui Xue
wiley   +1 more source

Global deep-sea hydrothermal deposit metagenomes and metagenome-assembled genomes over time and space. [PDF]

Sci Data
St John E, Reysenbach AL.
europepmc   +1 more source

A Physics Constrained Machine Learning Pipeline for Young's Modulus Prediction in Multimaterial Hyperelastic Cylinders Guided by Contact Mechanics

Advanced Intelligent Discovery, EarlyView.
A physics‐guided machine learning framework estimates Young's modulus in multilayered multimaterial hyperelastic cylinders using contact mechanics. A semiempirical stiffness law is embedded into a custom neural network, ensuring physically consistent predictions. Validation against experimental and numerical data on C.
Christoforos Rekatsinas, Panagiotis Krokidas, Vasileios Vavourakis, Clara Essmann, George Giannakopoulos   +4 more
wiley   +1 more source

Mining and engineering of ene-reductases from marine sediment metagenome for prochiral ACE inhibitor synthesis. [PDF]

Appl Environ Microbiol
Zou Y, Zhou J, Zeng Y, Chen B, Liu L, Xu G.   +5 more
europepmc   +1 more source

Toward Knowledge‐Guided AI for Inverse Design in Manufacturing: A Perspective on Domain, Physics, and Human–AI Synergy

Advanced Intelligent Discovery, EarlyView.
This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee, Hyeonbin Moon, Junhyeong Lee, Seunghwa Ryu   +3 more
wiley   +1 more source

Drifting in the abyss: an in-situ observation of swimming in <i>Psychropotes</i> (Psychropotidae, Elasipodida, Holothuroidea). [PDF]

Mar Biodivers
Bribiesca-Contreras G, Mackenzie M, Kremenetskaia A, Van Audenhaege L, Fleming BFM, Glover AG, Simon-Lledó E, Jones DOB.   +7 more
europepmc   +1 more source