Results 141 to 150 of about 14,363,927 (258)

Audio Signal Analysis using Deep Learning

reservedGoal of the work is to develop and improve a tool for automated Transcription of Audiosignals using deep learning techniques. Approaches should be used which restrict the output to a predefined vocabulary.
HOETH, MAX HENNING
core  

Combined Deep and Shallow Knowledge in a Unified Model for Diagnosis by Abduction [PDF]

Fault Diagnosis in real systems usually involves human expert’s shallow knowledge (as pattern causes-effects) but also deep knowledge (as structural / functional modularization and models on behavior).
Florin Postolache, Viorel Ariton
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The Mechanisms of Deep Earthquakes [PDF]

This dissertation uses a variety of seismological and mathematical tools to investigate the mechanisms of deep earthquakes, the properties of fault planes and rupture at high pressure within the Earth, and the local conditions where deep earthquakes ...
Myhill, Robert
core  

Endoscopic resection for verrucous venous malformation and capillary arteriovenous malformation: a deep approach to superficial lesions. [PDF]

Front Surg
Guo Z, Xie C, Lin W, Wang P, Yang W, Wang H.   +5 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

A hybrid deep approach to recognizing student activity and monitoring health physique based on accelerometer data from smartphones. [PDF]

Sci Rep
Xiao L, Luo K, Liu J, Foroughi A.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Examining the links between achievement goals, students' approaches to learning, and learning outcomes in business studies. [PDF]

Front Psychol
Ojala H, Tuominen H, Niemivirta M, Huikku J.   +3 more
europepmc   +1 more source