Results 121 to 130 of about 4,865,431 (261)

Computational Investigation of Adaptive Deep Brain Stimulation

, 2015
Deep Brain Stimulation of the sub-thalamic nucleus (STN) has been proven to be effective at reducing symptoms of patients with Parkinson's disease (PD).
Thang, CY, Paul A. Meehan, Meehan, PA, Christopher Y. Thang   +3 more
core   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

Deep-brain-stimulation does not impair deglutition in Parkinson's disease.

, 2012
peer reviewedOBJECTIVE: A large proportion of patients with Parkinson's disease develop dysphagia during the course of the disease. Dysphagia in Parkinson's disease affects different phases of deglutition, has a strong impact on quality of life and may ...
Rommel, N., Gasser, T., Wächter, T., Kipping, Judy, Rommel, Natalie, Kipping, J., KRÜGER, Rejko, Breit, S., Breit, Sorin, Plewnia, Christian, Weiß, Daniel Timo, Plewnia, C., Krüger, R., Weiss, D., Lengerer, Sabrina, Weiss, Daniel, Gasser, Thomas, Wachter, Tobias, Lengerer, S.   +18 more
core   +1 more source

Programming Neuromorphic Plasticity Through Ionic and Electronic Coupling in Organic Electrochemical Transistors

Advanced Functional Materials, EarlyView.
Neuromorphic plasticity in OECTs is governed by the post‐stimulus evolution of coupled ionic and electronic states. Semiconductor chemistry and morphology, electrolyte composition and interfaces, and device architecture regulate ion injection, transport, confinement, and release, shifting responses from rapidly relaxing STP to metastable memory and ...
Inho Lee, Hyoik Jang, Ji Hwan Kim, Jonghyun Won, Namhee Kim, Wonseok Shin, Giwon Lee, Eunho Lee, Daegun Kim, Sungjun Park   +9 more
wiley   +1 more source

Long-term Outcome of Globus Pallidus Internus Deep Brain Stimulation in Patients With Tourette Syndrome

, 2014
Objective: To evaluate the effectiveness of deep brain stimulation (DBS) of the globus pallidus internus (GPi) on tic severity and common comorbidities in patients with severe Tourette syndrome that is refractory to pharmacological treatment and ...
Stead, Matt, Zhang, Jian-Guo, Hu, Wei, Ge, Yan, Yan, Shuang-shuang, Zhang, Kai, Meng, Fan-Gang   +6 more
core  

Effectiveness of deep brain stimulation in alleviating treatment-resistant schizophrenia: a systematic review

European Journal of Translational Myology
The complexity of schizophrenia, particularly in cases resistant to traditional pharmacological treatments, poses significant challenges for clinicians and researchers.
Mohsen Khosravi
doaj   +1 more source

Beyond Primary Nucleation: Molecular Basis of Peptide Crystal Secondary Nucleation at Soft Interface

Advanced Functional Materials, EarlyView.
High spatiotemporal‐resolution atomic force microscopy directly resolved peptide secondary nucleation (SN) and growth characteristics and mechanisms on HOPG. The landscape of peptide nucleation sites, growth dynamics, molecular‐scale structures, phase transitions, and cross‐seeding processes were realized.
Linhao Sun, Abilesh Kumar, Ayhan Yurtsever   +2 more
wiley   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Numerical investigation of the electric field distribution induced in the brain by transcranial magnetic stimulation

, 2004
Results are presented on the prediction and optimisation of the electric field distribution obtained during transcranial magnetic stimulation (TMS) for deep neuron stimulation by using the finite-element method (FEM) in three dimensions.
Kim, D., Loukaides, N., Georghiou, G. E., Sykulski, J.K.   +3 more
core