Results 221 to 230 of about 315,574 (256)

Rare Abdominal Manifestations in a Patient with Parkinson's Disease after Deep Brain Stimulation of the Subthalamic Nucleus: A Case Report. [PDF]

Case Rep Neurol
Koyama H, Morigaki R, Miyake K, Matsuda T, Fujikawa J, Shinohara K, Nishida Y, Takagi Y.   +7 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Impedance Problems and Their Causes-A Single-Center Analysis of 601 Patients with De Novo Deep Brain Stimulation. [PDF]

J Clin Med
Fortmann T, Zawy Alsofy S, Santacroce A, Nakamura M, Ewelt C, Lehrke R.   +5 more
europepmc   +1 more source

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

Advanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy, Heta Helakari, Tommi Väyrynen, Zalán Rajna, Niko Huotari, Lauri Raitamaa, Ville Isokoski, Matti Järvelä, Mika Kaakinen, Johanna Piispala, Mika Kallio, Vesa Korhonen, Tapio Seppänen, Vesa Kiviniemi   +13 more
wiley   +1 more source

Impact of levodopa and deep brain stimulation on visual impairments in Parkinson's disease. [PDF]

Clin Park Relat Disord
Aslam S, Olson M, Kovacs M, Ansari P, Karukote A, Chan J, Barbu S, Felsen S, Shill HA, Adler CH.   +9 more
europepmc   +1 more source

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

Effect of deep brain stimulation on early-onset Parkinson's disease with mutations in a Han Chinese Mainland population. [PDF]

BMC Neurol
Chen S, Yang N, Liu J, Xu S, Xu S, Wang J, Li C, Liu YM.   +7 more
europepmc   +1 more source

Clinical utility of evoked potentials for programming subthalamic deep brain stimulation in Parkinsons disease. [PDF]

NPJ Parkinsons Dis
Hale B, Latorre A, Rocchi L, Rothwell J, Limousin P.   +4 more
europepmc   +1 more source

Prefrontal Network Mechanisms of Psychiatric Deep Brain Stimulation. [PDF]

J Neurosci
Glewwe N, Grissom NM, Widge AS.
europepmc   +1 more source