Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Interleaved stimulation in globus pallidus internus deep brain stimulation in a case of adult-onset Huntington's disease. [PDF]
Liu K +6 more
europepmc +1 more source
Neuroendoscopy-compatible neurostimulation catheter for minimally-invasive and multifunctional hypothalamic deep brain stimulation. [PDF]
Park JY +6 more
europepmc +1 more source
An Improved Beta Burst Extraction for Chip-Based Deep Brain Stimulation With Real-Time Model Updating. [PDF]
Ou-Yang YH +5 more
europepmc +1 more source
Foslevodopa/Foscarbidopa Subcutaneous Infusion Safety and Efficacy in Patients with and Without Prior Deep Brain Stimulation. [PDF]
Henriksen T +11 more
europepmc +1 more source
Deep brain stimulation for Meige syndrome. [PDF]
Jaffee S +4 more
europepmc +1 more source
A Reflection on Movement Disorders Fellowship Training in Deep Brain Stimulation: Past and Future. [PDF]
Shah-Zamora D, Mahajan A, Sarva H.
europepmc +1 more source
Rescue Thalamotomy for Habituation to Deep Brain Stimulation in Essential Tremor: Case Report. [PDF]
Kiselev R, Babchenko V.
europepmc +1 more source
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Mechanisms of deep brain stimulation
Movement Disorders, 2002The mechanism of action of high frequency deep brain stimulation is still unknown. However, in all circumstances and in all target nuclei so far stimulated, the effects mimic those of lesions previously made during thalamotomies, pallidotomies or even subthalamotomies, suggesting an inhibition of at least the neuronal network containing the target, if ...
Jonathan O Dostrovsky
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Neuroimaging of Deep Brain Stimulation
Neurologic Clinics, 2020Deep brain stimulation is the most advanced and effective neuromodulation therapy for Parkinson disease, essential tremor, and generalized dystonia. This article discusses how imaging improves surgical techniques and outcomes and widens possibilities in translational neuroscience in Parkinson disease, essential tremor, generalized dystonia, and ...
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