Results 111 to 120 of about 13,010 (279)

Prospective cohort of deep dyspareunia in an interdisciplinary setting

, 2018
Introduction: Deep dyspareunia is a common symptom in women, including in half of women with endometriosis, but little is known about its response to treatment and predictors of persistent deep dyspareunia over time.
Bodmer-Roy, Sonja, Britnell, Susannah, Arion, Kristina, Wong, Fontayne, Yager, Holly, Lisonkova, Sarka, Noga, Heather, Brotto, Lori A., Yong, Paul J., Ezeigwe, Chukwuemeka, Williams, Christina, Yosef, Ali, Bedaiwy, Mohamed Ali, 1968-, Albert, Arianne, Zhu, Sean, Ambacher, Kristin, Allaire, Catherine   +16 more
core   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

The role of 3.0T MRI in the assessment of deep endometriosis located on the uterosacral ligaments

, 2013
Purpose: To assess the diagnostic accuracy of 3.0T magnetic resonance imaging (MRI) in assessing the involvement of uterosacral ligaments (USLs) in deep infiltrating endometriosis (DIE). Methods: Between July 2010 and July 2012, 42 women, aged between 19
MANGANARO, Lucia, BERNARDO, SILVIA, SERGI, MARIA ELEONORA, BRUNELLI, Roberto, TICINO, ADELE, FUGGETTA, ELIANA, BENEDETTI PANICI, PIERLUIGI, SOLLAZZO, PAOLO, Paola Storelli, VINCI , VALERIA, PORPORA, Maria Grazia   +10 more
core   +1 more source

Core stability in women with and without chronic pelvic pain

PM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin, Abhilasha Kumar, Michael Wesolowski, Laura Glaser, Colleen M. Fitzgerald, Stacey Bennis   +5 more
wiley   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Factors Associated With Hormone Replacement Therapy Use: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To identify factors associated with HRT uptake among women. Design A systematic review and meta‐analysis to identify factors associated with HRT uptake. Setting Retrospective and prospective cohort studies, case–control studies and cross‐sectional studies from any country and in any language. Population The study population was women
Wema Meranda Mtika, Deborah Allen, Eve Tranter, Grace Glover, Janice Hoang, Sarah Hillman, Carol Coupland, Julia Hippisley‐Cox, Lynn Tatnell, Jennifer A. Hirst   +9 more
wiley   +1 more source

Symptom Flares in Endometriosis: Burden, Self‐Management and Barriers to Care in a Cross‐Sectional Survey

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore the characteristics of symptom flares, individual experiences and behaviours during flares in people with endometriosis. Design Online questionnaire shared on patient support sites. Setting People with a confirmed or working diagnosis of endometriosis (a working diagnosis is given by clinicians based on symptoms/history ...
Lydia Coxon, Emma Evans, Francine Toye, Emma Cox, Katy Vincent   +4 more
wiley   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Factors Associated With Menopause Symptoms: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Menopause, marked by hormonal decline and menstrual cessation, is associated with various symptoms. Socio‐demographic and behavioural factors may influence symptom type and severity. Understanding these associations can inform better symptom management.
Janice Hoang, Kathryn Halliday, Deborah Allen, Wema Meranda Mtika, Eve Tranter, Grace Glover, Lynn Tatnell, Julia Hippisley‐Cox, Carol Coupland, Sarah Hillman, Jennifer Hirst   +10 more
wiley   +1 more source