Complement Factor H‐Based Therapeutics: A Comprehensive Overview
Complement factor H is a central regulator of the complement system and thus a target for therapeutic intervention. In this review, we provide an overview of past and current factor H‐based therapeutic concepts and modalities to treat complement‐mediated diseases.
Sebastiaan M. W. R. Hamers +2 more
wiley +1 more source
Changes in the M1/M2 ratio due to andrographolide therapy for deep endometriosis: An experimental study using a BALB/C endometriosis model. [PDF]
Susianto IA +3 more
europepmc +1 more source
Bifidobacterium breve B2798 Attenuates Diet‐Induced Obesity Through Gut‐Adipose Crosstalk
ABSTRACT Obesity is driven by complex interactions between diet, gut microbiota, and host metabolism. Here, we investigate whether the probiotic Bifidobacterium breve B2798 mitigates high‐fat diet (HFD)‐induced metabolic dysfunction in C57BL/6J mice. Male mice received HFD for 12 weeks, followed by 12 weeks of B. breve B2798 or saline.
Yue Zhao +5 more
wiley +1 more source
Gastrointestinal function outcomes following radical and conservative colorectal surgery for deep endometriosis: A systematic review and meta-analysis. [PDF]
Darici E +5 more
europepmc +1 more source
Abstract Objective Combined oral contraceptives (COCs) for dysmenorrhea management have been covered by the Japanese universal health insurance system since 2008. Several public awareness events regarding COC prescriptions for dysmenorrhea were implemented between 2013 and 2015, including media reports on COC‐related fatalities in 2013, drug safety ...
Risa Ishida +8 more
wiley +1 more source
Totally intracorporeal colorectal anastomosis (TICA) after segmental colorectal resection for deep endometriosis: technical notes and case series. [PDF]
Santullo F +10 more
europepmc +1 more source
This retrospective cohort study included 350 individuals who underwent cesarean section. Data from 198 participants who met the inclusion criteria were analyzed. The region below ROC curves for the sliding sign was 0.717 (95% CI: 0.645–0.789). The sensitivity was 58.9%, specificity was 84.6%, positive predictive value (PPV) was 81.7%, negative ...
Can Ata +3 more
wiley +1 more source
Diagnostics and Surgical Treatment of Deep Endometriosis-Real-World Data from a Large Endometriosis Center. [PDF]
Grube M +10 more
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) in the mammalian oviduct constitute a key maternal regulatory system that maintains redox balance during early embryogenesis, yet their molecular cargo and functional relevance in human embryos remain poorly defined.
Yuehan Li +13 more
wiley +1 more source
Decidualized ovarian and rectouterine deep endometriosis disguised as malignancy in the second-trimester of pregnancy: A case report. [PDF]
Bao L +7 more
europepmc +1 more source

