Results 221 to 230 of about 54,282 (300)

Clinical Characterization of Patients With 5q Spinal Muscular Atrophy Types 2 and 3 in Brazil: A Cross‐Sectional Observational Study

open access: yesClinical Genetics, EarlyView.
This study describes the clinical heterogeneity of Brazilian patients with 5q spinal muscular atrophy types 2 and 3, highlighting prolonged diagnostic delays and the impact of disease duration on motor function. Early genetic diagnosis and access to multidisciplinary care are crucial to preserve functional outcomes.
Elice Carneiro Batista   +31 more
wiley   +1 more source

Irradiated Liver Cancer Cell Vaccine Transfected With GM‐CSF Induces Specific and Long‐Lasting Anti‐tumour Immunity Through the Synergistic Effect of Oxidised mtDNA and GM‐CSF

open access: yesCell Proliferation, EarlyView.
Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song   +15 more
wiley   +1 more source

Catheter Ablation: Evolution and Efficiencies

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

[Reconstruction of the deep femoral artery].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1981
J E, Fossdal   +3 more
openaire   +1 more source

A Comprehensive Assessment of Renal Function During and After Pulsed Field Ablation

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Acute kidney injury is an uncommon complication of pulsed field ablation (PFA). There is, however, limited empirical data on the dynamics of renal biomarkers apart from creatinine. Furthermore, no study to date has assessed creatinine at more than 24 h after the procedure. Methods Patients undergoing PFA for atrial fibrillation (AF)
Václav Melenovský   +10 more
wiley   +1 more source

Sustained Idiopathic Outflow Tract Ventricular Tachycardia: Clinical Evidence for RVOT Predominance

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Idiopathic outflow tract premature ventricular contractions (PVCs) are most commonly localized in the right ventricular outflow tract (RVOT). The clinical significance of sustained outflow tract ventricular tachycardia (OT‐VT) regarding any predominance to one specific anatomic area remains uncertain.
Moneeb Khalaph   +16 more
wiley   +1 more source

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