Results 161 to 170 of about 37,520 (250)

Pristimerin Attenuates Fibrogenesis and Inflammation Through TIPE1‐Regulated P2X7r Inflammatory Signaling Cascades in Hepatic Fibrosis

Phytotherapy Research, EarlyView.
ABSTRACT Pristimerin (Pris), a natural triterpenoid extracted from Celastrus orbiculatus Thunb. and Gymnosporia acuminata Hook. f., has various pharmacological activities, including anti‐inflammatory and anti‐tumor effects. Our study explored the influence of Pris on fibrogenesis and inflammatory modulation via the tumor necrosis factor‐alpha‐induced ...
Guan‐Cheng Liu, Qi‐Yuan Feng, Shuya Li, Yue Shang, Xin Guo, Hai‐Ming Sun, Yu‐Chen Jiang, Jian Song   +7 more
wiley   +1 more source

Oxyberberine Ameliorates Type 2 Diabetic Osteoporosis Through Sirtuin 3‐Associated Regulation of Autophagy and Ferroptosis in Bone Marrow Mesenchymal Stem Cells

Phytotherapy Research, EarlyView.
Schematic overview of the in vivo and in vitro experimental designs used to investigate the protective effects of oxyberberine (OBB) against type 2 diabetic osteoporosis, including C‐Z treatment, Sirt3 knockdown, and assessments of osteogenesis, autophagy, oxidative stress, and ferroptosis. ABSTRACT Type 2 diabetic osteoporosis (T2DOP) is characterized
Jianan Huang, Baihao Chen, Hua Zhang, Junzheng Yang, Jiacong Xiao, Chenhui Meng, Yanchao An, Kai Meng, Baohua Wang, Zhantian An, Peng Chen   +10 more
wiley   +1 more source

Engineering ApoE‐Mimetic HDL‐Like Nanoparticles for Glioblastoma‐Targeted Theranostics

Small Methods, EarlyView.
An ApoE‐mimetic peptide enables the stable formation of sub‐30 nm HDL‐like nanoparticles (ApoEm‐PLP) that simultaneously engage multiple lipoprotein receptors. This multivalent receptor interaction facilitates the transport of ApoEm‐PLP into brain and enhances targeted delivery of ApoEm‐PLP to glioblastoma, resulting in uniform intratumoral porphyrin ...
Hanyi Weng, Rick Wentao Cui, Ling Xi Gong, Ashley Qian, Lili Ding, Nahyun Kwon, Yiming Yang, Yulin Mo, Tiffany Ho, Madeline K. Brown, Maneesha Amrita Rajora, Juan Chen, Gang Zheng   +12 more
wiley   +1 more source

Anatomical Variations Encountered During the Posterior Approach to the Hip Joint. [PDF]

J Funct Morphol Kinesiol
Katsogiannis D, Triantafyllou G, Koutserimpas C, Demetriou F, Georgiev GP, Tsakotos G, Valenzuela-Fuenzalida JJ, Sanchis-Gimeno J, León-Rojas JE, Piagkou M.   +9 more
europepmc   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

Veterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin, Ariadne Rein, Isabella de Almeida Fabris, Beatriz Gasser, Luiz Paulo Nogueira Aires, Bruna Bressianini Lima, Daniele Azevedo Gandra, Daniela Gomes da Silva, Ricardo Andrés Ramirez Uscategui, Gabriela Castro Lopes Evangelista, Marcus Antônio Rossi Feliciano, Paola Castro Moraes   +11 more
wiley   +1 more source

Retained Guidewire Following Perforator Vein Ablation. [PDF]

Cureus
Sanka S, Chait J, Ascher E, Hingorani A.
europepmc   +1 more source

Perioperative analgesia and postoperative motor function after saphenous and sciatic nerve blocks in goats undergoing bilateral stifle surgery: A pilot study

Veterinary Record, EarlyView.
Abstract Background The combination of femoral and sciatic nerve blocks offers adequate perioperative analgesia for goats undergoing stifle surgery. However, postoperatively, residual motor dysfunction may lead to distress and discomfort. This study evaluated whether combined saphenous and sciatic nerve blocks provide adequate perioperative analgesia ...
Xavier Torruella, Claire Loughran, Flavia Restitutti, Joei Potter, Margot C. Labberté, Pieter A. J. Brama, Vilhelmiina Huuskonen   +6 more
wiley   +1 more source

Soft-tissue Coverage for Complex Knee Defects: The Role of Microsurgery in Optimizing Functional Limb Salvage. [PDF]

Plast Reconstr Surg Glob Open
Galvano E, Kleiber GM, Parikh RP.
europepmc   +1 more source

Protodesnitazene: The identification and tissue distribution of a new nitazene

Journal of Forensic Sciences, EarlyView.
Abstract Multiple new analogues from the 2‐benzyl benzimidazole or “nitazene” class of drugs have emerged on the drug market in recent years. Nitazenes are highly potent μ‐opioid receptor agonists that present a substantial public health concern due to their elevated risk of severe toxicity in overdose and their significant potential for misuse.
Andrew Griffiths, Nathan Milne, Michelle Johnston, Karen Blakey, Rogan Scott   +4 more
wiley   +1 more source

Intracardiac thrombus and multiple venous thromboses revealing focal segmental glomerulosclerosis. [PDF]

CEN Case Rep
Hamzaoui M, Machmachi I, Amar K, Hamdi F, Harmouch T, Haddiya I, Bentata Y.   +6 more
europepmc   +1 more source