Results 51 to 60 of about 8,607,090 (295)

Numerical Analysis of Influences of Engineering Piles for Anti-Inrush of Deep Excavation under Confined Water

open access: yesAdvances in Civil Engineering, 2023
Aiming at the problem of anti-inrush of confined water in foundation pits considering the influence of engineering piles, a three-dimensional numerical analysis model of anti-inrush stability of deep foundation pits is established by using the finite ...
Zehai Cheng   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Centrifugal model tests on characteristics of deep foundation pits in starting well of shield tunneling machine

open access: yesYantu gongcheng xuebao
In order to explore the stress, deformation and soil pressure distribution of the surrounding soils during the excavation process of deep foundation pits in starting well of the shield tunneling machine, two sets of centrifugal model tests are conducted ...
SUN Hui 1, LI Bo 1, WANG Zhipeng 2, WANG Shuai 1
doaj   +1 more source

Monitoring and numerical simulation of support for foundation pit at Yanyuan Road Station of Lanzhou Metro

open access: yesYantu gongcheng xuebao, 2021
The unique water-rich red sandstone stratum in Lanzhou area is easy to disintegrate when excavated and exposed, and the excavation and dewatering of foundation pits are extremely difficult.There is still no complete design and construction experience for
YIN Li-jie 1, 3, LI Yu-jie 2, ZHU Yan-peng 2, HUO Bin 4, YANG Zhi-tuan 4, DUAN Qin-chuan 4
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Case Study on the Deformation Coupling Effect of a Deep Foundation Pit Group in a Coastal Soft Soil Area

open access: yes, 2022
Simultaneous construction of adjacent projects may lead to emergencies in a foundation pit group, which significantly affects the deformation and safety of foundation pits. In this study, the deformation characteristics of a deep foundation pit group and
Shangrong Chen, Fayun Liang, Jifei Cui
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Experimental Study on the Variation Law of Excess Pore Water Pressure at the Bottom of the Foundation Pit for Excavation

open access: yesAdvances in Materials Science and Engineering, 2020
The excavation unloading of deep foundation pits in soft soil areas often produces negative excess pore water pressure. The rebound deformation of soil on the excavation surface of the foundation pit can be predicted reliably through the accurate ...
Qizhi Hu   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Displacement analysis and numerical simulation of pile-anchor retaining structure in deep foundation pit [PDF]

open access: yes
Foundation pit excavation can cause settlement and displacement of surrounding existing buildings and roads. In order to study the influence of soil unloading on the surrounding buildings during pit foundation excavation, the application of a pile-anchor
Yin, Xupeng, Ni, Hongmei
core   +1 more source

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