Results 141 to 150 of about 20,846,472 (359)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Unveiling the role of industries for European financial stability. Insights from the energy sector
Journal of Business Economics and ManagementExtensive analysis of intertwinement with other industries caused the energy sector to gain momentum in the recent economic literature. This paper aims to create an indicator that captures the impact of financial stability for energy companies on all ...
Iulia Lupu, Radu Lupu, Adina Criste
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Estimating urban noise levels from Multi-Scale and Multi-Spectral remote sensing imagery
International Journal of Applied Earth Observations and GeoinformationEstablishing a high-quality urban sound environment is essential for the sustainable development of modern cities. Estimating the noise pollution levels in urban areas is integral to improving the overall well-being of city dwellers.
Zhihong Chen +5 more
doaj +1 more source
Hybrid Macro/Micro Level Backpropagation for Training Deep Spiking\n Neural Networks [PDF]
, 2018 Yingyezhe Jin, Wenrui Zhang, Peng Li
openalex +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
On several correlation integrals of the deep level transients [PDF]
, 2003 Pham Quoc Trieu, Hoang Nam Nhat
openalex +1 more source