Results 141 to 150 of about 6,045 (287)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Comment les médias grand public alimentent-ils le populisme de droite? [PDF]
, 2019 The vertiginous rise of right-wing populism, especially in its “nationalist, xenophobic and conservative form”, and some “racist, anti-Semitic, homophobic and sexist” drifts associated with this phenomenon – whether real or perceived as such – make the ...
Farte, Gheorghe-Ilie
core
Covid-19: The cultural constructions of a global crisis. [PDF]
Int J Cult Stud, 2022 Frosh P, Georgiou M.
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Migrants in the public discourse: Between media, policy and public opinion [PDF]
, 2017 The chapter focuses on the public and political discourse on “migrants” in Europe, which frames the relationship between migrants and trade unions, and offers an overview of the main issues at stake.
Giorgi, Alberta, Vitale, Tommaso
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Information System: Transport Dynamic Cartography in Alsace. [PDF]
, 2007 International audienceThe issue of the presented work is to publish on line a dynamic cartography system of the transport traffic evaluation, based upon the Alsace (France) regional level experiment.
Masselot, Cyril, Quoy, Oliver
core +2 more sources
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
'Aquí viene una Veneca más': Venezuelan migrants and 'the sexual question' in Peru. [PDF]
Anthropol Med, 2022 Irons R.
europepmc +1 more source