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Deep Learning Architectures For the Prediction of YY1-Mediated Chromatin Loops

2022
Abstract YY1-mediated chromatin loops play substantial roles in basic biological processes like gene regulation, cell differentiation, and DNA replication. YY1-mediated chromatin loop prediction is important to understand diverse types of biological processes which may lead to the development of new therapeutics for neurological ...
Ahtisham Fazeel Abbasi   +4 more
openaire   +1 more source

Biological mediation in ocean crust alteration: how deep is the deep biosphere?

Earth and Planetary Science Letters, 1999
Abstract Biological mediation has been suggested as a control of the chemical exchange between the oceanic crust and seawater, but very little is known about its distribution within the oceanic crust and the relative importance of biotic and abiotic processes.
Harald Furnes, Hubert Staudigel
openaire   +1 more source

Deep Eutectic Solvent‐Mediated Regioselective Synthesis of Imidazoheterocycles

Macromolecular Symposia, 2021
AbstractAn environmentally benign methodology for the regioselective synthesis of an important class of imidazoheterocycles has been developed using choline chloride‐based deep eutectic solvent. It involves the coupling of 2‐amnopyrimidines, 2‐aminopyridines, and 2‐aminopyrazines with 2‐halocarbonyl compounds to get a variety of substituted ...
Dattatray B. Yedage, Dattatray V. Patil
openaire   +1 more source

Adenosine is crucial for deep brain stimulation–mediated attenuation of tremor

Nature Medicine, 2007
Deep brain stimulation (DBS) is a widely used neurosurgical approach to treating tremor and other movement disorders. In addition, the use of DBS in a number of psychiatric diseases, including obsessive-compulsive disorders and depression, is currently being tested.
Lane, Bekar   +11 more
openaire   +2 more sources

Deep-penetrating photodynamic therapy with KillerRed mediated by upconversion nanoparticles

Acta Biomaterialia, 2017
The fluorescent protein KillerRed, a new type of biological photosensitizer, is considered as a promising substitute for current synthetic photosensitizes used in photodynamic therapy (PDT). However, broad application of this photosensitiser in treating deep-seated lesions is challenging due to the limited tissue penetration of the excitation light ...
Liang, Liuen   +7 more
openaire   +5 more sources

Deep Strain-Mediated Thermal Transport in Silicon Nanowires

Nano Letters
The ability to tune thermal transport through strain engineering offers transformative potential for advanced nanodevices, yet the impact of deep elastic strains (>5%) remains largely unexplored due to challenges in experimental implementation. Here we address this gap by developing a MEMS-based platform to probe strain-thermal transport coupling in ...
Yanchao Li   +6 more
openaire   +2 more sources

Spinal Micturition Reflex Mediated by Afferents in the Deep Perineal Nerve

Journal of Neurophysiology, 2005
Reflexes mediated by urethral sensory pathways are integral to urinary function. This study investigated the changes in bladder pressure and urethral sphincter activity resulting from electrical stimulation of afferents in the deep perineal nerve (DP), which innervates the urethra and surrounding muscles, before and after acute spinal cord transection
Joseph W, Boggs   +3 more
openaire   +2 more sources

Rapid transfer of oxygen to the deep ocean mediated by bubbles

Nature Geoscience, 2020
The concentration of oxygen exerts major controls on life in the ocean, and its distribution in the ocean and atmosphere carries information about biological productivity, transports of mass and heat, ocean deoxygenation and global carbon sinks. Our understanding of processes underlying oxygen distributions, their key features and variability is often ...
D. Atamanchuk   +3 more
openaire   +1 more source

An apparent, deep-seated, carbonium-mediated sesquiterpene rearrangement

The Journal of Organic Chemistry, 1985
Mecanisme de la transposition de la methylene-3 octahydro-trimethyl-5,5,9, benzocycloheptenone-7 en hexahydro tetramethyl-3,3,5,7 ethano-4,7 indenone ...
Goverdhan Mehta   +5 more
openaire   +1 more source

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