Results 81 to 90 of about 6,045 (287)

The Trials of Media Research [PDF]

open access: yes, 2018
Media research is a vexing enterprise. Trapped in the borderlands between social science and the humanities, the study of media and communication bears the liabilities of both.
Jefferson Pooley
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The European Union’s Democratic Deficit and Options for EU Democracy in the 21st Century. EU Centre Singapore Working Paper No. 22, August 2014 [PDF]

open access: yes, 2014
The European Union (EU) is widely acknowledged as a successful example of economic and political integration of nation states today – a slate of democratic institutions such as the European Parliament have also been developed and European citizens now ...
Lee, Dexter
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Changes in Young People’s Media Repertoires. Longitudinal Insights from a Communicative Figurational Approach

open access: yesMedien & Kommunikationswissenschaft
Young people use digital media for various purposes, such as communication, entertainment, and information. As they grow up, their media repertoires become more complex and diverse.
Katrin Potzel   +4 more
doaj   +1 more source

Starving for Justice: Bangladeshi garment workers in a 'Post-Rana Plaza' world [PDF]

open access: yes, 2015
This review was published in the International Labor and Working-Class History [© 2015 International Labor and Working-Class History, Inc.] and the definite version is available at: http://doi.org/10.1017/S0147547915000101 The article website is at ...
Siddiqi, Dina Mahnaz
core   +1 more source

Deep Mediatization, Platforms and Logjects

open access: yes, 2021
In this article, we aim to understand how the notion of deep mediatization, proposed by Couldry and Hepp, can be an important reference for communication studies, taking into account the nature of platforms and digital objects. In this direction, it was also necessary to reflect on the cultural forms assumed by these new communicational environments ...
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Digital Traces in Context| Digital Traces in Context — An Introduction

open access: yesInternational Journal of Communication, 2018
A consequence of living in a media-saturated world is that we inevitably leave behind digital traces of our media use. In this introduction to the International Journal of Communication’s thematic section, we argue for a need to put those digital traces
Andreas Hepp   +2 more
doaj  

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