Results 111 to 120 of about 4,786,586 (290)

Simulation Experiment of Environmental Impact of Deep-Sea Mining: Response of Phytoplankton Community to Polymetallic Nodules and Sediment Enrichment in Surface Water. [PDF]

Toxics, 2022
Ou R, Cai L, Qiu J, Huang H, Ou D, Li W, Lin F, He X, Wang L, Wu R.   +9 more
europepmc   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Experimental Study on the Shear Characteristics of Deep-Sea Sediments Based on a Mining Machine Walking Test Platform

Advances in Civil Engineering
The exploitation and utilization of deep-sea mineral resources is an important measure to ensure the safety of resources. The shear characteristics of deep-sea sediments are fundamental parameters for the design of a machine for mining polymetallic ...
Xiaoyan Li, Lang Lei, Shengwei Zhao, Jenisha Singh, Zhou Li   +4 more
doaj   +1 more source

Numerical simulations and large-scale experimental research into air-lifting system for deep-sea mining

International Journal of Naval Architecture and Ocean Engineering
The deep seabed harbors abundant mineral resources. To achieve the economic viability of deep-sea mining, the efficiency of polymetallic nodule lifting is critical.
JianYu Xiao, Zhuang Kang, Jing Leng, Ming Chen, Jun Liu   +4 more
doaj   +1 more source

High‐Throughput Screening for Accelerated Oxide Glass Discovery

Advanced Science, EarlyView.
A high‐throughput screening platform is presented that allows for accelerating laboratory glass synthesis by a factor of 102, using multicomponent stereolithographic printing. Automatic sample evaluation is achieved via Raman spectroscopy and similarity analysis without any sample preparation.
Igor Seibel‐Geraschenko, Josef Slowik, Franziska Scheffler, Alexis Duval, N. M. Anoop Krishnan, Lothar Wondraczek   +5 more
wiley   +1 more source

Real-Time Prediction of the Dynamic Spatial Configuration of Umbilical Cables Based on Monitoring Data During Deep-Sea In-Situ Mining

Journal of Marine Science and Engineering
Prediction of the spatial configuration of the umbilical cable during deep-sea mining in-situ tests is of great significance because dynamic change may cause the umbilical cable to touch the ground or overturn the mining vehicle.
Chaojun Huang, Shuqing Wang, Jiancheng Liu, Lei Li, Wencheng Liu, Lin Huang, Zhihao Yu, Wen Shen, Yuankun Sun, Yu Liu, Yuanyuan Liu   +10 more
doaj   +1 more source

A Scalable Spin‐Coating Strategy for Mesoporous Gold Thin Films toward miRNA Detection

Advanced Science, EarlyView.
A scalable spin‐coating strategy produces uniform mesoporous Au thin films with tunable thickness and high electroactive surface area on transparent substrates. The resulting architecture enables label‐free, amplification‐free detection of ovarian cancer‐associated miRNA hsa‐miR‐200c‐3p from 1 aM to 10 pM, achieving a 1.72 aM detection limit with high ...
Aditya Ashok, Emtiaz Ahmed, Arya Vasanth, Mandy Hei Man Leung, Miharu Eguchi, Md Shahriar A. Hossain, Mostafa Kamal Masud, Carlos Salomon, Yusuke Yamauchi   +8 more
wiley   +1 more source

Feasibility study on manganese nodules recovery in the Clarion-Clipperton Zone

, 2012
The sea occupies three quarters of the area on the earth and provides various kinds of resources to mankind in the form of minerals, food, medicines and even energy.
Zhou, Jenny Jin, Placidi, Marco, Santo, Harrif, Agarwal, Baivau, Hu, Pan   +4 more
core   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

Design of a Novel Diamine Biosensor to Guide the Engineering of Escherichia coli for Cadaverine Overproduction

Advanced Science, EarlyView.
A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng, Getao Liu, Ding Ma, Jiaxiang Yuan, Xinyi Zhang, Weihao Wang, Chen Ma, Yang Liao, Siyuan Gao, Lei Qin, Jiao Feng, Sheng Xu, Xin Wang, Kequan Chen   +13 more
wiley   +1 more source