Results 81 to 90 of about 241,296 (309)

Biotechnological aspects of sulfate reduction with methane as electron donor [PDF]

open access: yes, 2010
Biological sulfate reduction can be used for the removal and recovery of oxidized sulfur compounds and metals from waste streams. However, the costs of conventional electron donors, like hydrogen and ethanol, limit the application possibilities.
Lens, P.N.L.   +2 more
core   +2 more sources

SiCmiR Atlas: Single‐Cell miRNA Landscape Reveals Hub‐miRNA and Network Signatures in Human Cancers

open access: yesAdvanced Science, EarlyView.
SiCmiR predicts mature miRNA activity at single‐cell resolution using only 977 landmark genes, enabling scalable reconstruction of miRNA landscapes across diverse tissues and disease contexts. The SiCmiR Atlas integrates 9.36 million cells with analytical tools for hub‐miRNA discovery, biomarker prioritization, and regulatory network interrogation ...
Xiao‐Xuan Cai   +12 more
wiley   +1 more source

Recent Advances in Decoupling Strategies for Soft Sensors

open access: yesAdvanced Science, EarlyView.
This review provides an overview of recent advances in decoupling strategies for soft sensors. It summarizes single‐modal sensors that are insensitive to stretching, bending, crosstalk, and other environmental interferences, and highlights emerging multimodal decoupling methods enabled by spatiotemporal information and machine learning.
Yangbo Yuan   +4 more
wiley   +1 more source

A dataset describing chip parameters for rock breaking by chisel pick under deep-sea hydrostatic pressure

open access: yesScientific Data
Chip is a visual representation of rock breaking by cutter, and their related parameters are crucial for revealing the rock breaking mechanism in deep-sea mining.
Zenghui Liu   +5 more
doaj   +1 more source

Experimental device for simulating reverberation environment in deep sea mining

open access: yes工程科学学报, 2017
To solve the difficult problem of ultrasonic signal acquisition with respect to real-time tiny terrain detection in the deep-sea mining environment, an experimental ultrasonic detection system was designed and built that can simulate the real deep-sea ...
HAO Qi   +3 more
doaj   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

open access: yesAdvanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo   +3 more
wiley   +1 more source

Optimal control of the heave motion of marine cable subsea-unit systems [PDF]

open access: yes, 1995
One of the key problems associated with subsea operations involving tethered subsea units is the motions of support vessels on the ocean surface which can be transmitted to the subsea unit through the cable and increase the tension.
Huang, S., Vassalos, D.
core  

Characterization and evolution of the sediments of a Mediterranean coastal lagoon located next to a former mining area [PDF]

open access: yes, 2015
Coastal lagoons are ecosystems that are relatively enclosed water bodies under the influence of both the terrestrial and themarine environment, being vulnerable to human impacts.
García Fernández, Gregorio   +1 more
core   +2 more sources

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

open access: yesAdvanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li   +16 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu   +6 more
wiley   +1 more source

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