Results 51 to 60 of about 72,783 (306)

Effect of Intraoperative Propofol-Induced Sedation on the Neurotransmitter Levels (Pilot Study)

Общая реаниматология, 2021
The aim of the study was to determine the changes in the levels of various neurotransmitters depending on the depth of propofol-induced sedation.Material and methods. Twenty-four patients were included in a prospective, simple blinded study. All patients
V. O. Churakov, A. Yu. Zaitsev, O. V. Dymova, K. V. Dubrovin, S. G. Zhukova, N. A. Matveeva   +5 more
doaj   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

The influence of different application patterns of propofol on the sedation courses during drug‐induced sleep endoscopy

Laryngoscope Investigative Otolaryngology
Objective The course of sedation during drug‐induced sleep endoscopy (DISE) depends on the application pattern of the sedative drug. The depth of sedation should imitate light and deep sleep as well.
Yehor Polievoi, Daniel Grafmans, Mariia Skliar, Andrea Kossatz, Jens Soukup, Patrick Kellner, Beatrice Herzog, Michael Herzog   +7 more
doaj   +1 more source

Clinical analysis of moderate-to-deep-sedation by nonmedical sedation practitioners in 597 patients undergoing gastrointestinal endoscopy: a retrospective study

Endoscopy International Open, 2016
Background and study aim: The purpose of this study was to evaluate whether moderate-to-deep sedation with propofol and alfentanil can be administered safely by nonmedical sedation practitioners, and the outcomes of this practice in the Netherlands.
Hermanus Vaessen, Elisabeth Bruens, Johannes Knape   +2 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Who Receives Home-Based Perinatal Palliative Care: Experience from Poland [PDF]

, 2013
The current literature suggests that perinatal palliative care (PPC) programs should be comprehensive, initiated early, and integrative. So far there have been very few publications on the subject of home-based PC of newborns and neonates.
Korzeniewska-Eksterowicz, Aleksandra, Kędzierska, Bogna, Młynarski, Wojciech, Przysło, Łukasz, Stolarska, Małgorzata   +4 more
core   +4 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Comparison between the recovery time of alfentanil and fentanyl in balanced propofol sedation for gastrointestinal and colonoscopy: a prospective, randomized study [PDF]

, 2012
BACKGROUND: There is increasing interest in balanced propofol sedation (BPS) titrated to moderate sedation (conscious sedation) for endoscopic procedures.
Chia-Ming Yen, Chin-Hung Lan, Chung-Yi Lin, Kai-Lin Hwang, Ming-Chih Chou, Su-Boon Yong, Wai-Meng Ho   +6 more
core   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Trends in Dental Sedation Permits in Select U.S. States, 2015–2023

Journal of the California Dental Association
Background Sedation is used in dentistry to manage anxiety, facilitate treatment and improve patient comfort during invasive procedures. While it can enhance acceptance of care, variations in state regulations and training requirements influence ...
Ansen Zhi-Han Lai, Jean Marie Star
doaj   +1 more source