Results 11 to 20 of about 240,068 (314)
Identification of Tox chromatin binding properties and downstream targets by DamID-Seq
Genomics Data, 2016 In recent years, DNA adenine methyltransferase identification (DamID) has emerged as a powerful tool to profile protein-DNA interaction on a genome-wide scale.
António Miguel de Jesus Domingues +3 more
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Metagenomic Analysis of Marigold: Mixed Infection Including Two New Viruses
Viruses, 2021 Marigold plants with symptoms of mosaic, crinkle, leaf curl and necrosis were observed and small RNA and ribo-depleted total RNA deep sequencing were conducted to identify the associated viruses.
Hang Yin +7 more
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Scoring protein sequence alignments using deep learning [PDF]
Bioinformatics, 2021 Abstract Motivation A high-quality sequence alignment (SA) is the most important input feature for accurate protein structure prediction. For a protein sequence, there are many methods to generate a SA.
Bikash Shrestha, Badri Adhikari
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Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc
eLife, 2018 As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis +6 more
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Deep learning in next-generation sequencing
Drug Discovery Today, 2021 Next-generation sequencing (NGS) methods lie at the heart of large parts of biological and medical research. Their fundamental importance has created a continuously increasing demand for processing and analysis methods of the data sets produced, addressing questions such as variant calling, metagenomic classification and quantification, genomic feature
Bertil Schmidt, Andreas Hildebrandt
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Registered report: Transcriptional amplification in tumor cells with elevated c-Myc
eLife, 2015 The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
David Blum +3 more
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eLife, 2017 Zebrafish display a distinct ability to regenerate their heart following injury. However, this ability is not shared by another teleost, the medaka.
Shih-Lei Lai +8 more
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MPL membrane domain sequencing goes deep [PDF]
Blood, 2020 In this issue of Blood, Bridgford et al1 present the first systematic approach to uncover all possible activating single point mutations within and around the transmembrane domain (TMD) of the thrombopoietin receptor (TpoR; also known as MPL). Several canonical activating MPL mutations (S505N and W515K/L/A/R) have been discovered through structure ...
Constantinescu, Stefan N. +1 more
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Mutational Analysis of Extranodal NK/T-Cell Lymphoma Using Targeted Sequencing with a Comprehensive Cancer Panel [PDF]
Genomics & Informatics, 2016 Extranodal natural killer (NK)/T-cell lymphoma, nasal type (NKTCL), is a malignant disorder of cytotoxic lymphocytes of NK or T cells. It is an aggressive neoplasm with a very poor prognosis.
Seungkyu Choi +6 more
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Frontiers in Microbiology, 2022 Bovine rotavirus (BRV) causes massive economic losses in the livestock industry worldwide. Elucidating the pathogenesis of BRV would help in the development of more effective measures to control BRV infection. The MA-104 cell line is sensitive to BRV and
Gehad Elkady +16 more
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