Aedes aegypti mosquitoes exhibit decreased repellency by DEET following previous exposure. [PDF]
PLoS ONE, 2013 DEET (N,N-Diethyl-m-toluamide) is one of the most widely used mosquito repellents. Although DEET has been shown to be extremely effective, recent studies have revealed that certain individual insects are unaffected by its presence.
Nina M Stanczyk +3 more
doaj +3 more sources
DEET repels ORNery mosquitoes [PDF]
Proceedings of the National Academy of Sciences, 2008 DEET ([N-N]-diethyl-m-toluamide) is widely used around the world as a repellent for mosquitoes and other biting insects. It was originally identified by a structure–activity study using synthetic compounds (1). Recently, a number of new compounds with similar activity [e.g., picaridine (2)] have been identified, but DEET remains the gold standard ...
Pickett, J. A. +2 more
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Assessment of methods used to determine the safety of the topical insect repellent N,N-diethyl-m-toluamide (DEET) [PDF]
Parasites & Vectors, 2014 N,N-diethyl-m-toluamide (DEET) has been registered for commercial use as an insect repellent for over five decades, and is used widely across the world.
Vanessa Chen-Hussey +2 more
doaj +2 more sources
The mysterious multi-modal repellency of DEET [PDF]
Fly, 2015 DEET is the most effective insect repellent available and has been widely used for more than half a century. Here, I review what is known about the olfactory and contact mechanisms of DEET repellency. For mosquitoes, DEET has at least two molecular targets: Odorant Receptors (ORs) mediate the effect of DEET at a distance, while unknown chemoreceptors ...
DeGennaro, Matthew
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Avoiding DEET through Insect Gustatory Receptors [PDF]
Neuron, 2010 DEET is the most widely used insect repellent worldwide. In Drosophila olfactory receptor neurons (ORNs), DEET is detected through a mechanism employing the olfactory receptor, OR83b. However, it is controversial as to whether ORNs respond directly to DEET or whether DEET blocks the response to attractive odors.
Lee, Youngseok +2 more
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Mosquito odorant receptor for DEET and methyl jasmonate [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance DEET ( N , N -diethyl-3-methylbenzamide) has intrigued medical entomologists, neurobiologists, insect physiologists, and chemical ecologists for decades, and hitherto it was not known how and why it works.
Xu, Pingxi +3 more
openaire +6 more sources
DEET-cyclodextrin inclusion complexes for mosquito and tick repellency: Extended repellency time and no zebrafish embryotoxicity. [PDF]
Pest Manag SciHydroxypropyl‐β‐cyclodextrin (HPβCD)–N,N‐diethyl‐meta‐toluamide (DEET) complex extended tick repellency to 168 h. Full protection against Aedes aegypti for 7 h with HPβCD‐DEET. HPβCD reduced DEET release and skin retention significantly. No embryotoxicity observed below 325 mg L−1 in zebrafish model.
Pereira GRS +10 more
europepmc +2 more sources
Transcriptional responses of Aedes aegypti chemosensory tissues in response to volatile DEET and citronella oil. [PDF]
Insect Mol BiolAedes aegypti females were significantly repelled by both volatile DEET and citronella oil in comparison to control (ethanol‐exposed) mosquitoes. Global gene expression changes were largest in the mosquito mouthparts, with notable downregulation of the three subunits comprising the mosquito CO2 receptor (Gr1, 2 and 3).
Drahun I +3 more
europepmc +2 more sources
Commercial permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages. [PDF]
Pest Manag SciAnopheles gambiae mosquitoes exhibit takeoff responses when presented to commercial permethrin headspace. This product elicits electrophysiological activity in the antennae and tarsi. However, only the chemical information acquired from the tarsi plays a major role in the observed behavioral response.
Kambou SS +4 more
europepmc +2 more sources
Multimodal targets of (-)-α-thujone mediating avoidance behavior of a stored-products pest, Tribolium castaneum, in response to irritant stimuli. [PDF]
Pest Manag SciWe identified four kinds of target molecules against (‐)‐α‐thujone associating avoidance behavior in Tribolium castaneum, indicating multimodality. Abstract BACKGROUND The reciprocal evolutionary processes among phytophagous insects and host plants involve host shift in the herbivorous insects in response to defense chemicals, such as plant‐derived ...
Shimomura K +4 more
europepmc +2 more sources