Results 91 to 100 of about 2,677,408 (327)
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
Forecasting Credit Portfolio Risk [PDF]
The main challenge of forecasting credit default risk in loan portfolios is forecasting the default probabilities and the default correlations. We derive a Merton-style threshold-value model for the default probability which treats the asset value of a ...
Hamerle, Alfred +2 more
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Could the subprime crisis have been predicted? A mortgage risk modeling approach [PDF]
, 2010 The abnormally high mortgage default rates that became apparent in early 2007 were not foreseen in June 2005, when mortgage production reached its peak.
Constantinou, Nick, Utrilla, Jose Molina
core
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
An Empirical Comparison of Default Swap Pricing Models [PDF]
In this paper we compare market prices of credit default swaps with model prices. We show that a simple reduced form model with a constant recovery rate outperforms the market practice of directly comparing bonds' credit spreads to default swap premiums.
Patrick Houweling, Ton Vorst
core
Where Fail-Safe Default Logics Fail
, 2004 Reiter's original definition of default logic allows for the application of a default that contradicts a previously applied one. We call failure this condition.
Cholewinski P. +8 more
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Secondary predication and default case [PDF]
, 2013 This paper compares secondary predication constructions (including small clause complements, resultatives, and/or depictives) in English and Korean and argues that these two typologically different languages employ different modes of satisfying the Case ...
Jang, Youngjun, Kim, Siyoun
core