Results 151 to 160 of about 716,083 (340)

Anatomia funzionale del Default Mode Network: studio della connettività funzionale in fMRI [PDF]

open access: yes, 2010
Il Default-Mode Network (DMN) è una rete di aree cerebrali maggiormente attive durante il riposo (resting) che vanno incontro a calo dell'attività (deattivazione) quando il cervello è chiamato a eseguire dei compiti. Queste aree svolgerebbero quindi una "
LEO, ANDREA
core  

Persistent default‐mode network connectivity during light sedation

open access: yesHuman Brain Mapping, 2008
Abstract The default‐mode network (DMN) is a set of specific brain regions whose activity, predominant in the resting‐state, is attenuated during cognitively demanding, externally‐cued tasks. The cognitive correlates of this network have proven difficult to interrogate, but one hypothesis is that regions in the network process ...
Michael D, Greicius   +6 more
openaire   +3 more sources

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

open access: yesAdvanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li   +19 more
wiley   +1 more source

Default mode network dynamics

open access: yesNeuroscience and Biobehavioral Reviews
Our intricate social brain is implicated in a range of brain disorders, where social dysfunction emerges as a common neuropsychiatric feature cutting across diagnostic boundaries. Understanding the neurocircuitry underlying social dysfunction and exploring avenues for its restoration could present a transformative and transdiagnostic approach to ...
Ronde, Mirthe   +2 more
openaire   +1 more source

Membrane Semi‐Permeability and Ion Selectivity in Chemiosmosis: Open Systems Volume Dependence of Electrolyte Chemistry

open access: yesAdvanced Materials Interfaces, EarlyView.
Very small cellular compartments can break electroneutrality and harness proton gradients without active transport structures, whereas larger volumes cannot, underscoring why life's critical energy processes are confined in microscopic spaces. ABSTRACT The effect of pH changes in external ionic solutions on liposomes entrapping non‐permeable weak acid ...
Josep M. Ribó   +4 more
wiley   +1 more source

Magnetic resonance spectroscopy demonstrates neuronal loss and altered glutamatergic neurotransmission in Alzheimer's Disease [PDF]

open access: yes, 2017
BACKGROUND: The role of the anterior cingulate cortex (ACC) is involved in the default mode network during resting state, and is dysfunctional in ageing and Alzheimer’s disease (AD).
Chiu, PWC   +4 more
core  

Ultra‐Improved Interfacial Strength Between Metallic Surface and Polyurethane via Cost‐Effective Anodizing Process

open access: yesAdvanced Materials Interfaces, EarlyView.
SAA significantly enhanced Al/PU bonding, increasing SLSS by up to 920% and fracture energy by 15 100% through optimized micro‐nano porous surfaces. RSM identified the optimal anodizing conditions, while ML confirmed sulfuric acid concentration and roughness as dominant predictors of strength.
Umut Bakhbergen   +6 more
wiley   +1 more source

Advanced Design for Weakly Coupled Resonators by Automatic Active Optimization

open access: yesAdvanced Materials Technologies, EarlyView.
An Automatic Active Optimization (AAO) strategy integrates machine learning predictors and genetic algorithms in a closed‐loop workflow. By iteratively expanding its dataset with new discoveries, AAO overcomes the limits of conventional methods. This approach finds superior microstructural designs beyond the initial sample space. We demonstrate this on
Wei Yue   +8 more
wiley   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

open access: yesAdvanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

White Matter Hyperintensity Load Modulates Brain Morphometry and Brain Connectivity in Healthy Adults: A Neuroplastic Mechanism?

open access: yesNeural Plasticity, 2017
White matter hyperintensities (WMHs) are acquired lesions that accumulate and disrupt neuron-to-neuron connectivity. We tested the associations between WMH load and (1) regional grey matter volumes and (2) functional connectivity of resting-state ...
Matteo De Marco   +3 more
doaj   +1 more source

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