Results 161 to 170 of about 88,203 (308)

Abnormal Enhanced Gamma Synchronization in the Default Mode Network Associated With Chronic Pain. [PDF]

Eur J Neurol
Jiang Z, Tao F, Lv F, Xu Z, Wang X, Cai Y, Du X, Sun F, Yi L, Liu S, Zhang X, Zheng Y, Gu W.   +12 more
europepmc   +1 more source

Learning from Default Mode Network: The Predictive Value of Resting State in Traumatic Brain Injury: Figure 1. [PDF]

, 2012
Stefano Sandrone, Marco Bacigaluppi
openalex   +1 more source

PSMD14‐Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression

Advanced Science, EarlyView.
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu, Li‐Kun Ren, Xiao‐Bin Fei, Song‐Bai Liu, Yong‐Jia Gao, Jun‐Yi Hou, Chi Wang, Peng Liu, Chang‐Hao Zhu, Xing Wang, Yao‐Zhen Pan   +10 more
wiley   +1 more source

IC‐01‐03: Molecular markers of Alzheimer's Disease pathology and their relationship with default mode network integrity

, 2011
Sofie Adriaanse, Ernesto Sanz‐Arigita, Maja Binnewijzend, Nelleke Tolboom, Alle Meije Wink, Ronald Boellaard, Maqsood Yaqub, Albert D. Windhorst, Wiesje M. van der Flier, Philip Scheltens, Adriaan A. Lammertsma, Frederik Barkhof, Bart van Berckel   +12 more
openalex   +1 more source

IC-O1-04: Beta-amyloid burden alters default mode and salience network connectivity associated with impaired cognition in healthy aging [PDF]

, 2012
Michael D. Devous, Kristen M. Kennedy, Karen M. Rodrigue, Andrew Hebrank, Denise C. Park   +4 more
openalex   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Default mode network connectivity in children with a history of preschool onset depression [PDF]

, 2012
Michael S. Gaffrey, Joan L. Luby, Kelly N. Botteron, Grega Repovš, M Deanna   +4 more
openalex   +1 more source

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

Advanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu, Sarah Golconda, Ga‐Eun Lee, Dantong Xue, Guillermo Domínguez‐Huerta, James M. Wainaina, Benjamin Bolduc, Shashanka Murthy, Shihyoung Kim, Seth Faith, Shan‐Lu Liu, Jiyoung Lee, Michael Oglesbee, Matthew B Sullivan, Sanggu Kim   +14 more
wiley   +1 more source

Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics

Advanced Science, EarlyView.
Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan, Enikő Zakar‐Polyák, Anita Adami, Anna A. Abbas, Yogita Sharma, Raquel Garza, Jenny G. Johansson, Diahann A. M. Atacho, Éva Renner, Miklós Palkovits, Csaba Kerepesi, Johan Jakobsson, Karolina Pircs   +12 more
wiley   +1 more source

Default mode network connectivity contributes the augment effect stress recovery by natural viewing. [PDF]

Neurobiol Stress
Chen Z, Wang C, Toulopoulou T, Chen X, Niu L, Dai H, Zhu Q, Zeng Y, Zhang R.   +8 more
europepmc   +1 more source