Results 191 to 200 of about 1,007,015 (362)

Topology of brain functional connectivity networks in posttraumatic stress disorder

Data in Brief, 2018
Here we present functional neuroimaging-based network data (focused on the default mode network) collected from a cohort of US Veterans with history of combat exposure, combined with clinical assessments for PTSD and other psychiatric comorbidities.
Teddy J. Akiki, Christopher L. Averill, Kristen M. Wrocklage, J. Cobb Scott, Lynnette A. Averill, Brian Schweinsburg, Aaron Alexander-Bloch, Brenda Martini, Steven M. Southwick, John H. Krystal, Chadi G. Abdallah   +10 more
doaj  

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Advanced Science, EarlyView.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu   +10 more
wiley   +1 more source

Numerical analysis of an extended structural default model with mutual liabilities and jump risk [PDF]

arXiv, 2016
We consider a structural default model in an interconnected banking network as in Lipton [International Journal of Theoretical and Applied Finance, 19(6), 2016], with mutual obligations between each pair of banks. We analyse the model numerically for two banks with jumps in their asset value processes.
arxiv  

Investigating the Functional Heterogeneity of the Default Mode Network Using Coordinate-Based Meta-Analytic Modeling [PDF]

, 2009
Angela R. Laird, Simon B. Eickhoff, Karl Li, Donald A. Robin, David C. Glahn, Peter T. Fox   +5 more
openalex   +1 more source

Comparison of Large Language Model with Aphasia

Advanced Science, EarlyView.
Large language models (LLMs) answer almost all questions fluently but often inaccurately, which resembles a specific type of aphasia in humans. Using a data‐driven analysis called energy landscape analysis, this study reveals similarities in the internal information dynamics between LLMs and the brains of humans with receptive aphasia, such as Wernicke'
Takamitsu Watanabe, Katsuma Inoue, Yasuo Kuniyoshi, Kohei Nakajima, Kazuyuki Aihara   +4 more
wiley   +1 more source

Lifespan differences in background functional connectivity of core cognitive large-scale brain networks

Neuroscience Research
Large-scale brain networks undergo functional reorganization over the course of the lifespan, with concurrent implications for cognition. Characterizing network connectivity during a task may provide complementary insight into cognitive development and ...
Patrick J. Pruitt, Lingfei Tang, Jessica M. Hayes, Noa Ofen, Jessica S. Damoiseaux   +4 more
doaj  

White matter microstructure underlying default mode network connectivity in the human brain [PDF]

, 2009
Stefan Teipel, Arun L.W. Bokde, Thomas Meindl, Edson Amaro, Jasmin Soldner, Maximilian F. Reiser, Sabine C. Herpertz, Hans‐Jürgen Möller, Harald Hampel   +8 more
openalex   +1 more source

MRAS: Master Regulator Analysis of Alternative Splicing

Advanced Science, EarlyView.
This study developed a computational approach called MRAS, designed to identify master regulators of splicing differences across various biological contexts. In this framework, altered RBP expression, rather than spliceosomal mutations or other modifications, plays a central role in driving these splicing differences.
Lei Zhou, Yue Huang, Yang Zhao, Dan Guo, Xiao Wen, Ruihong Xu, Xuan Lv, Song Wu, Sicheng Jing, Zhaoqi Liu   +9 more
wiley   +1 more source

Sustained activity within the default mode network during an implicit memory task [PDF]

, 2009
Jiongjiong Yang, Xuchu Weng, Yu‐Feng Zang, Mingwei Xu, Xiaohong Xu   +4 more
openalex   +1 more source

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

Advanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wang‐Sheng Wang   +8 more
wiley   +1 more source