Results 201 to 210 of about 320,501 (351)

Theta power during encoding predicts subsequent‐memory performance and default mode network deactivation [PDF]

, 2012
Thomas P. White, Marije Jansen, Kathrin Doege, Karen J. Mullinger, S. Bert Park, Elizabeth B. Liddle, Penny Gowland, Susan Francis, Richard Bowtell, Peter F. Liddle   +9 more
openalex   +1 more source

SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks

Advanced Science, EarlyView.
SCRIPT is a novel method inferring single‐cell cis‐regulatory relationships (CRRs) from transcriptomic and chromatin accessibility data. SCRIPT incorporates two key innovations: graph causal attention networks supported by empirical CRR evidence, and representation learning enhanced through pretraining on atlas‐scale single‐cell data.
Yu Zhang, Baole Wen, Yifeng Jiao, Yuchen Liu, Xin Guo, Yushuai Wu, Jiyang Li, Limei Han, Yinghui Xu, Xin Gao, Yuan Qi, Yuan Cheng, Ying He, Weidong Tian   +13 more
wiley   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Abnormal Enhanced Gamma Synchronization in the Default Mode Network Associated With Chronic Pain. [PDF]

Eur J Neurol
Jiang Z, Tao F, Lv F, Xu Z, Wang X, Cai Y, Du X, Sun F, Yi L, Liu S, Zhang X, Zheng Y, Gu W.   +12 more
europepmc   +1 more source

Alterations in Default Mode Network Connectivity During Pain Processing in Borderline Personality Disorder [PDF]

, 2012
Rosemarie Kluetsch, Christian Schmahl, Inga Niedtfeld, Maria Densmore, Vince D. Calhoun, Judith K. Daniels, Anja Kraus, Petra Ludaescher, Martin Bohus, Ruth A. Lanius   +9 more
openalex   +1 more source

SURF: A Self‐Supervised Deep Learning Method for Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Science, EarlyView.
SURF is a robust reference‐free deconvolution tool that integrates high‐dimensional spatial transcriptomics gene expression analysis with self‐supervised deep learning, enabling effective modeling of non‐linear gene interactions and spot relationships.
Shuyu Liang, Zixia Zhou, Peng Huang, Junhu Fu, Jing Jiao, Yunxia Huang, Shichong Zhou, Guanlin Wang, Yuanyuan Wang, Yi Guo   +9 more
wiley   +1 more source

Mindfulness disposition and default-mode network connectivity in older adults [PDF]

, 2012
Ruchika Shaurya Prakash, Angeline A. De Leon, Maryanna Klatt, William B. Malarkey, Beth Patterson   +4 more
openalex   +1 more source

Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP‐43‐Positive Assemblies in Motor Neuron Disease

Advanced Science, EarlyView.
Single‐molecule fluorescence microscopy is combined with proteomic profiling to fingerprint the morphology and composition of TDP‐43 protein aggregates found in post‐mortem motor neuron disease brain tissues. Aggregate fingerprints can distinguish disease from control donors and detect unexpected TDP‐43 pathology in SOD1‐MND.
Dezerae Cox, Melanie Burke, Sara Milani, Matthew A White, Fergal M Waldron, Dorothea Böken, Evgeniia Lobanova, Jemeen Sreedharan, Jenna M Gregory, David Klenerman   +9 more
wiley   +1 more source

IC‐01‐03: Molecular markers of Alzheimer's Disease pathology and their relationship with default mode network integrity

, 2011
Sofie Adriaanse, Ernesto Sanz‐Arigita, Maja Binnewijzend, Nelleke Tolboom, Alle Meije Wink, Ronald Boellaard, Maqsood Yaqub, Albert D. Windhorst, Wiesje M. van der Flier, Philip Scheltens, Adriaan A. Lammertsma, Frederik Barkhof, Bart van Berckel   +12 more
openalex   +1 more source

The Default Mode Network and Related Right Hemisphere Structures may be the Key Substrates of Dementia [PDF]

, 2012
Donald R. Royall, Raymond F. Palmer, Eric D. Vidoni, Robyn A. Honea, Jeffrey M. Burns   +4 more
openalex   +1 more source