Results 221 to 230 of about 1,007,015 (362)

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

A Neuro-Dynamic Mathematical Model of Dream Formation and Spontaneous Cognitive Activity [PDF]

arXiv
This paper introduces a biomathematical model designed to describe the internal dynamics of dream formation and spontaneous cognitive processes. The model incorporates neurocognitive factors such as dissatisfaction, acceptance, forgetting, and mental activity, each of which is linked to established neural systems.
arxiv  

SSRP1/SLC3A2 Axis in Arginine Transport: A New Target for Overcoming Immune Evasion and Tumor Progression in Peripheral T‐Cell Lymphoma

Advanced Science, EarlyView.
Enhanced arginine uptake is a critical feature of metabolic reprogramming in PTCL, characterized by elevated expression of the arginine transporter SLC3A2. SLC3A2‐mediated arginine uptake facilitates PTCL proliferation and survival by enhancing OXPHOS metabolism and inducing immune evasion.
Yimin Ren, Lei Fan, Ling Wang, Yanping Liu, Jie Zhang, Boya Wang, Ruize Chen, Xiao Chen, Lingyu Zhuang, Yaping Zhang, Handong Sun, Jianyong Li, Wenyu Shi, Hui Jin   +13 more
wiley   +1 more source

Consistency and functional specialization in the default mode brain network

, 2008
Ben J. Harrison, Jesús Pujol, Marina López‐Solà, Rosa Hernández‐Ribas, Joan Deus, Héctor Ortiz, Carles Soriano‐Mas, Murat Yücel, Christos Pantelis, Narcı́s Cardoner   +9 more
openalex   +1 more source

Default mode network functional and structural connectivity after traumatic brain injury [PDF]

, 2011
David Sharp, Christian F. Beckmann, Richard Greenwood, Kirsi M. Kinnunen, Valérie Bonnelle, X. De Boissezon, Jane H. Powell, Serena J. Counsell, Maneesh C. Patel, Robert Leech   +9 more
openalex   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
wiley   +1 more source

All roads lead to the default-mode network—global source of DMN abnormalities in major depressive disorder

Neuropsychopharmacology, 2020
A. Scalabrini, B. Vai, S. Poletti, S. Damiani, C. Mucci, C. Colombo, R. Zanardi, F. Benedetti, G. Northoff   +8 more
semanticscholar   +1 more source

Default-Mode and Task-Positive Network Activity in Major Depressive Disorder: Implications for Adaptive and Maladaptive Rumination [PDF]

, 2011
J. Paul Hamilton, Daniella J. Furman, Catie Chang, Moriah E. Thomason, Emily L. Dennis, Ian H. Gotlib   +5 more
openalex   +1 more source

Inverse Design of Highly Deformable Mechanical Metamaterial Based on Partitional Semi‐Random Optimization

Advanced Science, EarlyView.
This research presents a novel optimization method for the inverse design of flexible mechanical metamaterials, enhancing traditional strategies by evaluating deformation in subregions. Combining simulated annealing with a genetic algorithm, it improves design efficiency and enables customizable deformation paths.
Xueqing Cao, Zeang Zhao, Panding Wang, Shengyu Duan, Hongshuai Lei   +4 more
wiley   +1 more source

Altered default-mode network in Cerebral Palsy

, 2008
Park H.J
openalex   +1 more source