Results 221 to 230 of about 320,501 (351)

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

Advanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu, Sarah Golconda, Ga‐Eun Lee, Dantong Xue, Guillermo Domínguez‐Huerta, James M. Wainaina, Benjamin Bolduc, Shashanka Murthy, Shihyoung Kim, Seth Faith, Shan‐Lu Liu, Jiyoung Lee, Michael Oglesbee, Matthew B Sullivan, Sanggu Kim   +14 more
wiley   +1 more source

Academic success and mental health: The paradox of Frontoparietal-Default Mode Network coupling among children facing poverty. [PDF]

Dev Cogn Neurosci
Pacheco S, Bunge SA, Ellwood-Lowe ME.
europepmc   +1 more source

Frontoparietal and default mode network connectivity varies with age and intelligence

Developmental Cognitive Neuroscience, 2021
M. DeSerisy, Bruce Ramphal, D. Pagliaccio, E. Raffanello, G. Tau, R. Marsh, J. Posner, A. Margolis   +7 more
semanticscholar   +1 more source

Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics

Advanced Science, EarlyView.
Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan, Enikő Zakar‐Polyák, Anita Adami, Anna A. Abbas, Yogita Sharma, Raquel Garza, Jenny G. Johansson, Diahann A. M. Atacho, Éva Renner, Miklós Palkovits, Csaba Kerepesi, Johan Jakobsson, Karolina Pircs   +12 more
wiley   +1 more source

Shared genetics and causal relationship between sociability and the brain's default mode network. [PDF]

Psychol Med
Fanelli G, Robinson J, Fabbri C, Bralten J, Mota NR, Arenella M, Rovný M, Sprooten E, Franke B, Kas M, Andlauer TFM, Serretti A.   +11 more
europepmc   +1 more source

The visual selectivity of the default mode network

Journal of Vision, 2019
Martin Szinte, Tomas Knapen, Daniel Marten van Es   +2 more
openaire   +2 more sources

Targeting RBM10‐Repressed RORB Activity in Liquid Condensates Inhibits Lysosomal Biogenesis and Neuroblastoma Progression via Affecting NF‐κB Signaling

Advanced Science, EarlyView.
This study identifies that RBM10 represses the transcriptional activity of RORB in liquid condensates, resulting in down‐regulation of NR1D1 and RIOK3 that further activates NF‐κB activity to facilitate lysosomal biogenesis and aggressive features of NB cells.
Yanhua Guo, Xiaojing Wang, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Jiaying Qu, Shunchen Zhou, Liduan Zheng, Qiangsong Tong   +9 more
wiley   +1 more source

Neural variability in the default mode network compresses with increasing belief precision during Bayesian inference. [PDF]

Cereb Cortex
Skowron A, Kosciessa JQ, Lorenz RC, Hertwig R, van den Bos W, Garrett DD.   +5 more
europepmc   +1 more source

Painting Peptides With Antimicrobial Potency Through Deep Reinforcement Learning

Advanced Science, EarlyView.
AMPainter is a powerful design model for ’painting’ the antimicrobial potency on any given peptide sequence, based on the strategy of virtual directed evolution and deep reinforcement learning. Abstract In the post‐antibiotic era, antimicrobial peptides (AMPs) are considered ideal drug candidates because of their lower likelihood of inducing resistance.
Ruihan Dong, Qiushi Cao, Chen Song
wiley   +1 more source

ZnO Quantum Dots@CsPbBr3 Poly‐Heterocrystalline Film Enables High‐Performance Floating‐Gate Transistor Arrays for Edge Computing

Advanced Science, EarlyView.
The ZnO QDs@CsPbBr3 poly‐heterocrystalline film, featuring a semi‐coherent interface, delivers high electrical conductivity and excellent photoelectric properties. Functioning as a floating gate in photosensitive transistors, it enables high hole storage at 1 V and achieves a conductivity ratio of ≈3.57×105.
Jiajun Xu, Bo Tong, Nian Dai, Tongjian Liu, Zhibo Liu, Dingdong Zhang, Yan Liang, Song Qiu, Lai‐Peng Ma, Jinhong Du   +9 more
wiley   +1 more source