Results 251 to 260 of about 106,291 (299)

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Transfer of motor learning is associated with patterns of activity in the default mode network. [PDF]

PLoS Biol
Rezaei A, Areshenkoff CN, Gale DJ, De Brouwer AJ, Nashed JY, Flanagan JR, Gallivan JP.   +6 more
europepmc   +1 more source

Motor and default mode network states of rest in frontal lobe epilepsy. [PDF]

Neuroimage Rep
Rashnavadi T, Casseb RF, Woodward KE, Federico P, Goodyear B.   +4 more
europepmc   +1 more source

Key role of the default mode network in transfer of motor learning from previous experience. [PDF]

PLoS Biol
Imamizu H, Kondo T.
europepmc   +1 more source

Default mode network connectivity contributes the augment effect stress recovery by natural viewing. [PDF]

Neurobiol Stress
Chen Z, Wang C, Toulopoulou T, Chen X, Niu L, Dai H, Zhu Q, Zeng Y, Zhang R.   +8 more
europepmc   +1 more source

Social Smiling and Laughter Are Linked to Enhanced Functional Brain Connectivity in Young Infants' Default Mode Network. [PDF]

Dev Psychobiol
Allison O, Kelsey C, Grossmann T.
europepmc   +1 more source

Shared genetics and causal relationship between sociability and the brain's default mode network. [PDF]

Psychol Med
Fanelli G, Robinson J, Fabbri C, Bralten J, Mota NR, Arenella M, Rovný M, Sprooten E, Franke B, Kas M, Andlauer TFM, Serretti A.   +11 more
europepmc   +1 more source