Results 221 to 230 of about 160,958 (306)

Integrative utilization of genomic resources for improved phylogenetic resolution in Sonerileae (Melastomataceae)

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Advances in new next‐generation sequencing (NGS) methods have revolutionized phylogenetics, yet challenges remain in effectively utilizing data from a wide range of sources. A well‐resolved and broadly sampled phylogeny for Sonerileae, the second‐largest tribe in Melastomataceae, is still lacking, hindering our understanding of its ...
Luo Chen   +6 more
wiley   +1 more source

Assessment of Genetic Correlations Between Tobacco or Alcohol Use and Neurodegenerative Diseases Using East Asian Genetic Ancestry Genome‐Wide Association Study Results

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent late‐onset neurodegenerative diseases worldwide. Both are influenced in part by genetic factors and are currently incurable. Tobacco and alcohol, the two most common substances used among the general adult population, are potential AD/PD risk factors and are also ...
Linda Wang   +3 more
wiley   +1 more source

Anisotropic NMR as a Crucial Tool for Differentiation of Epimers With High Conformational Flexibility

open access: yesAngewandte Chemie, EarlyView.
Epimer discrimination remains challenging due to subtle NMR differences. Here, we propose a methodology based on 13C‐RCSA and RDC anisotropic parameters, enabling the assignment of two flexible tetraprenyltoluquinol epimers (1a and 1b) with remote stereoclusters.
Juan Carlos C. Fuentes‐Monteverde   +6 more
wiley   +2 more sources

NUPACK: Computational Nucleic Acid Analysis and Design. [PDF]

open access: yesACS Synth Biol
Fornace ME   +6 more
europepmc   +1 more source

AI‐Driven Mapping of Seizure Spread Patterns

open access: yesAnnals of Neurology, EarlyView.
Objective The focus of epilepsy research has largely been on seizure onset; however, physicians typically examine the patterns of seizure spread past seizure onset as well. This study aims to align automated seizure analysis with clinical practice, leverage deep learning to standardize seizure annotations that varies among physicians, and understand ...
Andrew Y. Revell   +13 more
wiley   +1 more source

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh   +7 more
wiley   +1 more source

Large Language Model Chatbot Conversations vs Public Health Materials and Parental HPV Vaccination Intentions: A Randomized Clinical Trial.

open access: yesJAMA Netw Open
Sehgal NKR   +8 more
europepmc   +1 more source

Imprecision in tuberculosis infection outcomes: implications for non-inferiority vaccine trials. [PDF]

open access: yesInt J Epidemiol
Grint DJ   +6 more
europepmc   +1 more source

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