Results 151 to 160 of about 5,859,176 (265)
Advanced Science, EarlyView.Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li +10 more
wiley +1 more source
A Model of Mortgage Default [PDF]
This paper solves a dynamic model of a household's decision to default on its mortgage, taking into account labor income, house price, inflation, and interest rate risk.
John Y. Campbell, João F. Cocco
core
Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota
Advanced Science, EarlyView.Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal +25 more
wiley +1 more source
Impact of regulatory capital on bank interest margins: Moderating role of default risk. [PDF]
HeliyonBegum M, Rahman MM, Faruq MO.
europepmc +1 more source
Empirical estimation of default and asset correlation of large corporates and banks in India [PDF]
Estimation of default and asset correlation is crucial for banks to manage and measure portfolio credit risk. This would require studying the risk profile of the banks’ entire credit portfolio and developing the appropriate methodology for the estimation
Bandyopadhyay, Arindam, Ganguly, Sonali
core
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
The inverted U-shaped relationship between corporate social responsibility and default risk: The role of financing constraints. [PDF]
HeliyonWang W, Yang J.
europepmc +1 more source
Forecasting Credit Portfolio Risk [PDF]
The main challenge of forecasting credit default risk in loan portfolios is forecasting the default probabilities and the default correlations. We derive a Merton-style threshold-value model for the default probability which treats the asset value of a ...
Scheule, Harald +2 more
core
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source