Results 101 to 110 of about 694,171 (324)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Frontiers in Neuroscience, 2018 Against the background of an increasingly competitive market environment, the current study aimed to investigate whether and how victory and defeat, as two critical factors in competition outcomes, would affect consumers’ preference of unfamiliar brands.
Wenjun Yu +7 more
doaj +1 more source
Citizen Soldiers: The North Carolina Volunteers and the War on Poverty [PDF]
, 1999 During the summers of 1964 and 1965, more than 300 college students fanned out across the state of North Carolina in a bold campaign to defeat poverty and, as they saw it, to uplift the poor.
Korstad, Robert R., Leloudis, James L.
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Marc Bloch et L’Étrange défaite
Cahiers d’histoireMarc Bloch’s only foray into contemporary history, L'Étrange défaite remains a fundamental work on the sudden and unexpected disaster of June 1940. This is not a spontaneous outpouring, but rather a work drawn from Bloch’s experience as a researcher and ...
Carole Fink
doaj +1 more source
RUDN Journal of Agronomy and Animal Industries, 2014 Drawn attention to the increasing danger and harmfulness phomosis disease of potatoes, potatoes with lesions which may reduce its yield by 30-50%. A description of the signs of the disease in the form of ulceration and necrosis on tubers and diffuse ...
A A Kuzmichev, S V Maltsev, V N Zeyruk
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
eLife, 2013 A dramatic example of the ‘arms race’ between hosts and pathogens has been observed in the response of mice to the parasite that causes toxoplasmosis.
Michael L Reese
doaj +1 more source
Join Up, Scale Up: How Integration Can Defeat Disease and Poverty [PDF]
, 2011 This report addresses three of the core areas: primary healthcare, clean water and sanitation, and nutrition -- that are essential to achieving the MDGs. It highlights examples across 17 countries of how bringing different development approaches together
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source