Results 131 to 140 of about 677,450 (332)

Learning to Play Othello with N-Tuple Systems [PDF]

open access: yes, 2008
This paper investigates the use of n-tuple systems as position value functions for the game of Othello. The architecture is described, and then evaluated for use with temporal difference learning.
Lucas, Simon M
core  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Choosing Fair Lotteries to Defeat the Competition [PDF]

open access: yes
We study the following game: each agent i chooses a lottery over nonnegative numbers whose expectation is equal to his budget b_i. The agent with the highest realized outcome wins and agents only care about winning).
Conitzer, Vincent, Wagman, Liad
core   +1 more source

Grievance Procedures and the Democratization of American Life [PDF]

open access: yes, 1976
[Excerpt] No institution in the nation\u27s history has struggled so long and so valiantly for the democratization of American life as the organized labor movement.
Neufeld, Maurice F
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Social defeat stress induces liver injury by modulating endoplasmic reticulum stress in C57BL/6J mice

open access: yesScientific Reports
Social defeat stress is associated with endoplasmic reticulum (ER) stress, inflammation and apoptosis. ER stress is thought to contribute to many lifestyle diseases such as liver injury, cardiovascular dysfunction and depression.
XiaoLei Gao   +4 more
doaj   +1 more source

The Masculine Sea and the Impossibility of Awakening in Chopin's the Awakening [PDF]

open access: yes, 2012
Kate Chopin has a firm place in American women's writing. A persistent theme in her works is said to be women's emotional liberation. The Awakening (1899) as a feminist novel is no exception.
P, A. (Abbasi)
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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