Results 21 to 30 of about 1,895,832 (295)

Concurrent newborn hearing and genetic screening of common hearing loss variants with bloodspot-based targeted next generation sequencing in Jiangxi province

Frontiers in Pediatrics, 2022
Background and aimsConcurrent hearing and genetic screening of newborns have been widely adopted as an effective strategy in early diagnosis and intervention for hearing loss in many cities in China.
Haiyan Luo, Yan Yang, Xinrong Wang, Fangping Xu, Cheng Huang, Danping Liu, Liuyang Zhang, Ting Huang, Pengpeng Ma, Qing Lu, Shuhui Huang, Bicheng Yang, Yongyi Zou, Yanqiu Liu   +13 more
doaj   +1 more source

Untargeted Global Metabolomic Analysis Reveals the Mechanism of Tripropylamine-Enhanced Lycopene Accumulation in Blakeslea trispora

Frontiers in Bioengineering and Biotechnology, 2021
We previously determined that the cyclase inhibitor tripropylamine (TPA) significantly enhances lycopene accumulation in Blakeslea trispora. To elucidate the mechanism of TPA-enhanced lycopene accumulation, the untargeted metabolome of B.
Yanlong Wang, Yulong Wang, Yicun Wang, Xin Chen, Cunping Liu, Meng Zhang, Keying Liu, Yuechao Zhao, Zexu Li   +8 more
doaj   +1 more source

Lycopene Aggravates Acute Gastric Injury Induced by Ethanol

Frontiers in Nutrition, 2021
Lycopene is an important natural red pigment with strong singlet oxygen and peroxide free radical quenching ability. Ethanol directly destroys the epithelial cells of gastric mucosa, causing oxidative damage and inflammation.
Xin Chen, Yuechao Zhao, Keying Liu, Zexu Li, Xingru Tan, Yulong Wang, Na Gao, Chenming Liu, Xiaoqi Fang, Yanlong Wang   +9 more
doaj   +1 more source

Software Defect Association Mining and Defect Correction Effort Prediction [PDF]

, 2006
Much current software defect prediction work concentrates on the number of defects remaining in software system. In this paper, we present association rule mining based methods to predict defect associations and defect-correction effort.
Cartwright, MH, Mair, C, Shepperd, MJ, Song, Q   +3 more
core   +2 more sources

Single‐cell and spatial transcriptomics reveal the fibrosis‐related immune landscape of biliary atresia

Clinical and Translational Medicine, 2022
Background Biliary atresia (BA) is a devastating inflammatory and fibrosing cholangiopathy of neonates with unknown aetiology. We aim to investigate the relationship between these two main characteristics.
Chunjing Ye, Jiajie Zhu, Junfeng Wang, Deqian Chen, Lingdu Meng, Yong Zhan, Ran Yang, Shiwei He, Zifeng Li, Shuyang Dai, Yi Li, Song Sun, Zhen Shen, Yanlei Huang, Rui Dong, Gong Chen, Shan Zheng   +16 more
doaj   +1 more source

Semilocal defects [PDF]

Physical Review D, 1992
I analyze the interplay of gauge and global symmetries in the theory of topological defects. In a two-dimensional model in which both gauge symmetries and {\it exact} global symmetries are spontaneously broken, stable vortices may fail to exist even though magnetic flux is topologically conserved.
openaire   +4 more sources

Diagnostic Value and Effectiveness of an Artificial Neural Network in Biliary Atresia

Frontiers in Pediatrics, 2020
Objectives: Biliary atresia (BA) is a devastating pediatric liver disease. Early diagnosis is important for timely intervention and better prognosis.
Jia Liu, ShuYang Dai, Gong Chen, Song Sun, JingYing Jiang, Shan Zheng, YiJie Zheng, Rui Dong   +7 more
doaj   +1 more source

Evolution of proton-induced defects in a cryogenically irradiated p-channel CCD [PDF]

, 2016
P-channel CCDs have been shown to display improved tolerance to radiation-induced charge transfer inefficiency (CTI) when compared to n-channel CCDs. This is attributed to the properties of the dominant charge-trapping defect species in p-channel silicon
Gow, Jason, Hall, David, Holland, Andrew, Murray, Neil, Stefanov, Konstantin, Wood, Daniel   +5 more
core   +1 more source

A chromosome 1q22 microdeletion including ASH1L is associated with intellectual disability in a Chinese family

Molecular Cytogenetics, 2020
Background Copy number variants (CNVs) associated with developmental delay and intellectual disability (DD/ID) continue to be identified in patients. This article reports identification of a chromosome 1q22 microdeletion as the genetic cause in a Chinese
Hui Xi, Ying Peng, Wanqin Xie, Jialun Pang, Na Ma, Shuting Yang, Jinping Peng, Hua Wang   +7 more
doaj   +1 more source

A novel and recurrent KLHL40 pathogenic variants in a Chinese family of multiple affected neonates with nemaline myopathy 8

Molecular Genetics & Genomic Medicine, 2021
Background Nemaline myopathy 8 is a severe autosomal recessive muscle disorder characterized by fetal akinesia or hypokinesia, contractures, fractures, respiratory failure and swallowing difficulties apparent at birth.
Sheng Yi, Yue Zhang, Zailong Qin, Shang Yi, Haiyang Zheng, Jingsi Luo, Qifei Li, Jin Wang, Qi Yang, Mengting Li, Fei Chen, Qiang Zhang, Qinle Zhang, Yiping Shen   +13 more
doaj   +1 more source