Results 101 to 110 of about 557,137 (294)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Defect detection of friction stir welding based on deep learning and infrared imaging

Hanjie xuebao
To address the problem of insufficient detection accuracy of visual detection by visible light in surface defect identification of welded joints, which is mainly susceptible to factors, such as illumination variations, simple backgrounds, small defect ...
Daxin REN, Shengkai FU, Zichong LI, Gang SONG, Zhaodong ZHANG, Liming LIU   +5 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

NeRF-based defect detection

International Conference on Remote Sensing, Mapping, and Image Processing (RSMIP 2025)
6 pages, 11 figures, 2025 2nd International Conference on Remote Sensing, Mapping and Image Processing (RSMIP 2025)
Kirk Ding, Dawei Xiang, Yijiashun Qi, Ze Yang, Zunduo Zhao, Tianyao Sun, Pengbin Feng, Haoyu Wang   +7 more
openaire   +3 more sources

Dynamic Detection Device for Transverse Defects of Tubing

Shiyou jixie, 2018
To address the problem of low visibility and poor detection accuracy of traditional magnetic flux leakage detection device on the transverse and longitudinal defects of the tubing, a transverse defect detection device was designed. Based on the theory of
Ding Chao, Tang Donglin, Wang Bin, Zhang Wenwen   +3 more
doaj  

Cloud-Edge Collaborative Defect Detection Based on Efficient Yolo Networks and Incremental Learning

Sensors
Defect detection constitutes one of the most crucial processes in industrial production. With a continuous increase in the number of defect categories and samples, the defect detection model underpinned by deep learning finds it challenging to expand to ...
Zhenwu Lei, Yue Zhang, Jing Wang, Meng Zhou   +3 more
doaj   +1 more source

IR defect detection in metals

iScience
To achieve non-destructive testing using infrared thermal wave technology, we integrated heat transfer theory with image science, employing theoretical analysis, finite element numerical simulation, and infrared thermography experiments. Experiments were conducted at 80°C, 106°C, and 130°C, capturing surface temperature distributions. Analysis revealed
Ai, Chunming, Lin, Haichuan, Sun, Pingping, Zhang, Xin   +3 more
openaire   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source