Results 41 to 50 of about 1,994,533 (253)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Defect Tolerance in Hybrid nano/CMOS Architecture using Tagging Mechanism [PDF]

open access: yes, 2009
In this paper we propose two efficient repair techniques for hybrid nano/CMOS architecture to provide high level of defect tolerance at a modest cost.We have applied the proposed techniques to a lookup table(LUT) based Boolean logic approach.
Srivastava, Saket   +2 more
core   +2 more sources

A local defect resonance for linear and nonlinear ultrasonic thermography [PDF]

open access: yes, 2014
An efficient wave-defect interaction is the key to a high thermal response of flaws in ultrasonic thermography. To selectively enhance defect vibrations a concept of local defect resonance is developed and applied to ultrasonic activation of defects ...
Solodov, I., Rahammer, M., Busse, G.
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Building a Rule-Based Expert System to Enhance the Hard Disk Drive Manufacturing Processes

open access: yesIEEE Access
The manufacturing of hard disk drives involves the intricate assembly of numerous components, making the testing process time-consuming and resource intensive.
Suppakrit Kirdponpattara   +2 more
doaj   +1 more source

Cross–Project Defect Prediction With Respect To Code Ownership Model: An Empirical Study

open access: yese-Informatica Software Engineering Journal, 2015
The paper presents an analysis of 83 versions of industrial, open-source and academic projects. We have empirically evaluated whether those project types constitute separate classes of projects with regard to defect prediction.
Marian Jureczko, Lech Madeyski
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Software Measurement and Defect Prediction with Depress Extensible Framework

open access: yesFoundations of Computing and Decision Sciences, 2014
Context. Software data collection precedes analysis which, in turn, requires data science related skills. Software defect prediction is hardly used in industrial projects as a quality assurance and cost reduction mean. Objectives.
Madeyski Lech, Majchrzak Marek
doaj   +1 more source

Cost-Sensitive Machine Learning for Predicting Production Defects: a Novel Approach Based on MetaCost [PDF]

open access: yesپژوهش در مدیریت تولید و عملیات
Purpose: This paper aims to apply cost-sensitive machine learning (CSML) for predicting production defects in industrial processes to minimize the costs associated with false negatives.
Ahmad Jafarnejad   +2 more
doaj   +1 more source

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